Hoffmann-la Roche Inc.

Roche Vitamins Inc.

Mary-Helen Binger

Luis Pasamontes

Richard Anthony Chizzonite

Peter T Lomedico

Werner Altenburger

Stephen J McAndrew

Richard Allen Kramer

The invention provides an immunogenic polypeptide having the amino acid sequence

DNA encoding eimeria antigen

The invention provides an immunogenic polypeptide having the amino acid sequence ##STR1## and fragments thereof, which polypeptides are capable of inducing an immune response against Eimeria parasites, and the DNA encoding such polypeptides, as well as recombinant vectors and recombinant viruses containing the said DNA or fragments thereof and transformed microorganisms containing such vectors and viruses and coccidiosis vaccines comprising such polypeptides.

Coccidiosis vaccines

This invention provides DNA sequences coding for Eimeria surface antigens, recombinant vectors containing such DNA sequences, transformed microorganisms containing such vectors, and methods for producing the antigens using the transformed microorganisms. Methods are also provided for protecting poultry against coccidiosis using the Eimeria surface antigens. The surface antigens can be administered for such protection either as purified proteins or in the form of DNA encoding the proteins in a suitable viral vector such as vaccinia virus.

Recombinant coccidiosis vaccines

The invention provides an immunogenic polypeptide having the amino acid sequence ##STR1## which polypeptides are capable of inducing an immune response against Eimeria parasites, and the DNA encoding such polypeptides, as well as recombinant vectors and recombinant viruses containing the said DNA and transformed microorganisms containing such vectors and viruses and coccidiosis vaccines comprising such polypeptides.

Growing community of inventors

Hopewell, NJ, United States of America

Mary-Helen Binger