Chiron Corporation

Mary Ellen Wernette Hammond

Paul A Renhowe

Cynthia Shafer

Sabina Pecchi

Timothy D Machajewski

Organic compounds having the structural formula I are provided where the variables have the values described herein and Rand Rjoin together to form a 6 membered substituted or unsubstituted ring including at least one O, N, or S atom, and Z is an O, S, NH or NR group. Pharmaceutical formulations include the organic compound or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.

Heterocyclic compounds

Organic compounds having the structural formula I are provided where the variables have the values described herein and Rand Rjoin together to form a 6 membered substituted or unsubstituted ring including at least one O, N, or S atom, and Z is an O, S, NH or NR group.  Pharmaceutical formulations include the organic compound or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.

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Castro Valley, CA, United States of America

Mary Ellen Wernette Hammond