Research Corporation Technologies, Inc.

Other

Research Corporation Tech., Inc.

Crozer-Chester Medical Center

Marvin Louis Lewbart

Arthur G Schwartz

Magid A Abou-Gharbia

John R Williams

Daniel Swern, Deceased

Ann R Swern

Steroids of the formula: ##STR1## useful as cancer preventive agents, anti-obesity agents, anti-hyperglycemic agents, anti-aging agents, and anti-hypercholesterolemic agents and anti-auto-immune agents.

Derivatives of 5-androsten-17-ones and 5-androstan-17-ones

Compounds of the formulae: ##STR1## useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agent.

Steroids useful as anti-cancer and anti-obesity agents

Derivatives of 5-androsten-17 ones and 5-androstan-17-ones

##STR1## useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anit-hypercholesterolemic agent.

The present invention is directed to compounds of the formula. ##STR1## useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agent.

##STR1## useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agent.

Compounds of the formulae: ##STR1## useful as anti-obesity, anti-diabetic, anti-coronary and hypolipidemic agents.

5 .alpha.-pregnan-20-ones and 5-pregnen-20-ones and related compounds

Method for prophylaxis of obesity

Compounds of the formula: ##STR1## useful as anti-cancer agents, anti-obesity agents, anti-hyperglycemic agents, anti-aging agents, anti-hyperglycemic agents and anti-autoimmune agents.

Homoandrostan-17-one and homoandrosten-17-ones

Compounds of the formula: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.

16-substituted androstanes and 16-substituted androstenes

Compounds of the formulae: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.

17-Hydroxy-steroids

Novel prednisolone derivatives modified at C-17,C-20 and/or C-21 positions. Many of the compounds are anti-inflammatory agents which do not significantly suppress the pituitary-adrenal axis.

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Media, PA, United States of America

Marvin Louis Lewbart