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Marvin Charles

Robert W Coughlin

Billy R Allen

Insoluble supports are preactivated by precipitating thereon a hydrous metal oxide employing a hydrolysis reaction of a salt of said metal in the presence of said insoluble support. The resulting composite materials are employed as supports for immobilizing biologically active substances.

Method of immobilization of biologically active organic substances

A liquid stream containing the reactants is passed through a bed of enzyme catalyst, made up of enzymes bonded to small, dense particles of carrier or support materials, in a manner which causes the bed to expand or fluidize and a chemical reaction is thereby carried out in a process that is simultaneously free from limitations due to plugging and excessive pressure drop and which also has the advantage of the high mass transfer rates that can be realized between the liquid and small particles.

Method of carrying out enzyme catalyzed reactions

A liquid stream containing the reactants is passed through a bed of enzyme catalyst, made up of enzymes bonded to small, dense particles of carrier or support materials, in a manner which causes the bed to expand or fluidize and a chemical reaction is thereby carried out in a process that is simultaneously free from limitations due to plugging and excessive pressure drop and which also has the advantage of the high mass transfer rates that can be realized between the liquid and small particles. Reactions are carried out in this manner using enzymes bound to porous and non-porous inorganic supporting particles. This process has been employed for treating cheese whey with the enzyme lactase in a fluidized bed of inert particles to which the lactase is bound.

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Allentown, PA, United States of America

Marvin Charles