International Business Machines Corporation

Coris Bioconcept

Coris Bioconcept Sprl

Martina Hitzbleck

Emmanuel Delamarche

Govind V Kaigala

Robert Dean Lovchik

Pascal Y Mertens

Luc Gervais

Laetitia C Avrain

Thierry C Laurent

Valerie Smekens

Valérie Smekens

Laetitia Avrain

Thierry Laurent

A microfluidic device is provided. The microfluidic device has: a flow inlet and a flow outlet; a bypass channel defining a first flow path away from the flow inlet and toward the flow outlet; and an auxiliary channel defining a second flow path away from the flow inlet and toward the flow outlet, wherein the auxiliary channel defines a reagent area adapted to receive a reagent, and wherein the auxiliary channel joins the bypass channel at a primary junction downstream from the reagent area and upstream from the flow outlet.

Microfluidic device with auxiliary and bypass channels

A microfluidic surface processing system includes a microfluidic probe head having a processing fluid circuit configured to dispense a surface processing fluid from a processing fluid aperture thereof; a linkage mechanism, configured to apply a force to or modulate a force applied to the microfluidic probe head towards a surface to be processed; and a lifting fluid circuit integral with the microfluidic probe head and distinct from the processing fluid circuit, the lifting fluid circuit designed for dispensing a lifting fluid from a lifting fluid aperture thereof, with pressure such as to counter the force applied or modulated by the linkage mechanism, at the level of the surface.

Microfluidic surface processing systems with self-regulated distance-to surface control

A microfluidic device includes a first microchannel, a second microchannel, and a valve comprising at least an input port and an output port, the ports respectively connected to the first microchannel and the second microchannel, the valve designed to control a flow of a liquid along a flow direction (z) defined by the ports; wherein the valve further comprises one or more walls joining the ports and defining a hollow chamber that is wider than each of the microchannels in a direction perpendicular to the flow direction, the walls at least partly deformable along a deformation direction (&#x2212;y) intersecting the flow direction, such that the walls can be given at least a first deformation state and a second deformation state, such that the liquid can be pulled along the flow direction substantially more in the second deformation state than in the first deformation state.

Microfluidic device with deformable valve

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Rueschlikon, Switzerland

Martina Hitzbleck