Ethicon, Gmbh

Martin Stephenson

Shalaby Wahba Shalaby

Frank V Mattei

Namassivaya Doddi

Graham H Hartley, Deceased

Louise Schaap

Allin K Gordon

Composite suture of multifilament silk embedded in a highly flexible, hydrophobic highly deformable matrix made of thermoplastic elastomer. This suture exhibits minimal irritation to living tissue and retains its strength in vivo for extended periods of time and also retains the desirable handling qualities of silk. The suture is prepared by treating a multifilament silk suture with a solution of a suitable polymer in a solvent and heating the moving suture to obtain a continuous impregnation of the silk with the elastomer.

Composite sutures of silk and hydrophobic thermoplastic elastomers

An absorbable hemostatic composition for use in the control of osseous hemorrhage, comprising a biocompatible fatty acid salt in a biocompatible base, said composition having a putty-like consistency at room temperature. The preferred composition is one in which the fatty acid salt is calcium stearate.

Absorbable hemostatic composition

Multifilament suture strands are impregnated with an antimicrobial agent and top coated with a segmented polyurethane polymer. The coated sutures possess antimicrobial properties which are retained during use over extended periods of time.

Antimicrobial sutures

A surgical suture is coated with an ionically bonded block elastomeric copolymer of a polyquaternary polyurethane and a polyanionic polymer such as heparin. The coated suture is receptive to treatment with antimicrobial compounds to produce a suture having long-lasting antimicrobial properties which inhibit bacterial growth in and immediately around the suture. The coated suture is also receptive to dyes for the preparation of colored sutures. Surgical aids other than sutures such as films, fabrics, wound dressings and the like may be coated and rendered antimicrobial or colored in a like manner.

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Peterborough, Canada

Martin Stephenson