Gambro Lundia Ab

Gambro Lunia Ab

Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

Rheinisch-westfälische Technische Universität Hochschule (rwth) Aachen

Martin Rempfer

Bernd Krause

Markus Storr

Markus Hornung

Wolfgang Freudemann

Torsten Knoer

Joachim Loercher

Heinrich Behr

Ralf Flieg

Steffen Wagner

Michael Müller

Christian Oehr

Matthias Wessling

Sandra Homeyer

Cornelia Winz

Ralf Menda

Stefanie Votteler

Jan Swartjes

Manuela Klotz

Mehmet Yildirim

Isabelle Litzinger

Philipp Kuhn

Jakob Barz

Michael Kather

Vivian Stefan Kurbel

Michael Alders

Ilka Rose

Ben Elkin

Sarah Panowitz

The invention relates to a blood treatment device configured to dephosphorylate extracellular adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and/or lipopolysaccharide (LPS) in the blood of a patient in need thereof in an extracorporeal blood circuit, wherein the device comprises a matrix having alkaline phosphatase (AP) immobilized thereon. The invention further relates to an extracorporeal blood circuit comprising a blood treatment device of the invention and to the blood treatment device for use as a medicament or to methods of treating an infection, preferably a blood or systemic infection, such as sepsis, and/or for the treatment of sepsis-associated acute kidney injury (AKI).

Blood treatment device comprising alkaline phosphatase

The present invention relates to membranes being suitable e.g. for hemodialysis, hemodiafiltration, or hemofiltration of blood. The invention also relates to a process for the production of the membranes; and to devices comprising the membranes.

Permselective asymmetric membranes

A filter apparatus, a method for the manufacture of the filter apparatus, the use of the filter apparatus in medical, chemical and/or biotechnological applications, and an apparatus for use in the manufacture of the filter apparatus. The filter apparatus has a cylindrical housing and a plurality of hollow fibers. The hollow fibers are combined to form a bundle in the housing and are embedded and held in each case at the end sides in a molding compound. The filtrate space is filled with particles of a chemically or physically active substance.

Filter device combining beads and fibers

A separation material includes a matrix that is bound to a saccharide, enabling the separation from a liquid of substances that selectively bind the saccharide. A method for preparing the separation material and a method for separating substances from a liquid that selectively bind a saccharide of the separation material are also described. A device employs the separation material for separating from a liquid substances that selectively bind to the saccharide of the separation material.

Separation material

A separation material includes a saccharide bound via a linker to a matrix for enabling the separation from a liquid of substances that selectively bind to saccharide moieties. A method for preparing the material, a method for separating from a liquid substances that selective bind to saccharides, and a device including the separation material are also disclosed.

Separation material comprising saccharide ligands

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Gomaringen, Germany

Martin Rempfer