National University of Ireland, Galway

University of Galway

Martin O'Halloran

Mark Bruzzi

David Townley

Sean Cummins

Brian Shields

Ivan Keogh

Jimmy Edward Eaton-Evans

John Thompson

Tony O'Halloran

Jonathan Bouchier-Hayes

Giuseppe Ruvio

Faisal Sharif

Nigel Phelan

Stephen Cox

Marggie Jones

Emily Elizabeth Porter

Ian Stephen O'Brien

Peter Dockery

Ricardo Eleuterio

Prem Puri

Sarah Loughney

Guiseppe Ruvio

A device for occlusion of a body lumen comprises an implantable occlusion apparatus () operably attached to an elongated catheter member () configured for transluminal delivery and deployment of the occlusion apparatus in the body lumen. The occlusion apparatus comprises a radially expansible element () detachably attached to the elongated catheter member, and adjustable between a contracted orientation suitable for 10 transluminal delivery and a deployed orientation configured to occlude the body lumen, an energy delivery element () configured to deliver energy to surrounding tissue to heat the tissue, and a sensor () configured to detect a parameter of the wall of the body lumen. The energy delivery element () and sensor () are axially movable independently of the radially expansible element whereby, in use, the energy delivery 15 element and sensor can be transluminally retracted leaving the radially expansible element in-situ occluding the body lumen.

Implantable medical device

A method of treating a vessel in a subject comprises the steps of advancing a device distally across a treatment zone in a vessel, wherein the device comprises an elongated catheter having a lumen and a distal end, and a radially expansive treatment element disposed in the lumen and configured for axial movement relative to the catheter; deploying the radially expansive treatment element proud of the distal end of the catheter to radially expand and circumferentially impress against the vessel lumen at a distal end of the treatment zone; and withdrawing the deployed radially expansive treatment element proximally along the treatment zone with the treatment element circumferentially impressed against the vessel lumen to mechanically and circumferentially denude the treatment zone of the vessel. The radially expansive treatment element is then recaptured into the lumen of the catheter, before the device is withdrawn from the treated vessel.

Devices and methods for treating a vessel in a subject

An ablation probe (), comprising: an applicator () arranged to apply radiation to heat surrounding tissue; a feeding cable () arranged to supply electromagnetic energy to the applicator. The feeding cable comprises a distal portion () and a proximal portion (). The distal portion of the feeding cable has a distal cross sectional size and the proximal portion of the feeding cable has a proximal cross sectional size, wherein the distal cross sectional size is less that the proximal cross sectional size. The ablation probe further comprises a connector () arranged to mechanically and electrically couple the distal portion () of the feeding cable () to the proximal portion () of the feeding cable (). The connector comprises a joining member () comprising a proximal end () shaped to receive an end of the proximal portion () of the feeding cable and a distal end () shaped to receive an end of the distal portion () of the feeding cable.

Ablation probe

A device for occlusion of a body lumen including an implantable occlusion apparatus () operably attached to an elongated catheter member () configured for transluminal delivery and deployment of the occlusion apparatus in the body lumen. The occlusion apparatus includes a radially expansible element () detachably attached to the elongated catheter member, and adjustable between a contracted orientation for transluminal delivery and a deployed orientation configured to occlude the body lumen, an energy delivery element () configured to deliver energy to surrounding tissue to heat the tissue, and a sensor () configured to detect a parameter of the wall of the body lumen. The energy delivery element () and sensor () are axially movable independently of the radially expansible element whereby, in use, the energy delivery element and sensor can be transluminally retracted leaving the radially expansible element in-situ occluding the body lumen.

A microwave ablation probe (), comprising: an applicator () arranged to apply microwave radiation to heat surrounding tissue; a feeding cable () arranged to supply electromagnetic energy to the applicator; a coolant flow path () via which coolant is able to flow; and a choke arranged to reduce power reflected from the applicator () along the feeding cable (). The choke comprises a choke member () cooled by coolant flowing in the coolant flow path (). The choke member () extends between two points spaced apart in a direction having at least a component parallel to a longitudinal axis of the feeding cable. The choke member () comprises one or more turns extending around the longitudinal axis of the feeding cable. The choke member may be a spiral member ().

Microwave ablation probe

Devices, systems, and methods for specializing, monitoring, and/or evaluating therapeutic nasal neuromodulation are disclosed herein. A targeted neuromodulation system configured in accordance with embodiments of the present technology can include, for example, an evaluation/modulation assembly at a distal portion of a shaft and including a plurality of electrodes. The electrodes are configured to emit stimulating energy at frequencies for identifying and locating target neural structures and detect the resultant bioelectric properties of the tissue. The system can also include a console that maps locations of the target neural structures. The evaluation/modulation assembly can then apply therapeutic neuromodulation energy in a highly tailored neuromodulation pattern based on the mapped locations of the target neural structures. Accordingly, the system provides therapeutic neuromodulation to highly specific target structures while avoiding non-target structures to reduce collateral effects.

Devices, systems, and methods for specializing, monitoring, and/or evaluating therapeutic nasal neuromodulation

The present relates to a method, system and a device for non-invasive detection of urine flow from the bladder into the kidney(s). The method, system and device rely on measurements made at distinct time points and can be used to detect Vesicoureteral reflux. The method, system and device are designed to detect changes in urine volume in the ureter(s), bladder and/or kidney(s). The method and device measure conductivity changes by bioelectrical impedance or electrical impedance tomography technology.

Non-invasive detection of the backflow of urine

Growing community of inventors

Galway, Ireland

Martin O'Halloran