Warner-lambert Company

Martin M Rieger

Robert K Yang

Subraman R Cherukuri

Gul Mansukhani

Frank P Calabro

Milton Elefant

According to this invention a medicament containing gum having improved delivery properties is produced by utilizing a chewing gum composition having a moisture content not greater than 0.3% by weight which softens at 40.degree. C. to 60.degree. C. and has an equilibrium relative humidity lower than the ambient relative humidity as produced and combined with a powdered, insoluble medicament which has been co-spray dried with sugar.

Antacid chewing gum

The aluminum salt of saccharin and a method for its preparation are disclosed. Chewing gum compositions comprising the novel salt are prepared.

Aluminum salt of saccharin

Process for the preparation of the aluminum salt of saccharin

A non-steroidal anti-inflammatory composition comprising a therapeutically effective amount of active anti-inflammatory agent selected from the group consisting of 1-phenyl-1 cyclohexene, 4-phenylcyclohexanone, and mixtures thereof. The active agent may be formulated in a pharmaceutically acceptable carrier. These compositions are useful in the treatment in mammals of inflammation and other related symptoms, including pain.

Non-steroidal anti-inflammatory compounds and compositions thereof

Methods for treating inflammation

The present invention relates to a gum composition exhibiting improved shelf life and resistance to staling, that comprises a substantially anhydrous mixture of a gum base, at least one sugar alcohol, and glycerin, the glycerin present in an amount ranging from greater than 10% to about 18% by weight of the composition. The gum composition preferably contains no more than 2% by weight of water. The invention includes a method for preparing the gum composition, comprising treating the ingredients thereof, including the glycerin, to remove substantially all water therefrom, thereafter combining the sugar alcohol with the glycerin under agitation and at about 50.degree. C., and adding subsequently thereto the gum base, after which certain additive materials, such as flavorings, and the like may be added with mixing.

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Morris Plains, NJ, United States of America

Martin M Rieger