James Black Foundation Limited

Martin Lyn Hudson

Ildiko Maria Buck

Sarkis Barret Kalindjian

Iain Mair McDonald

Michael John Pether

Matthew John Tozer

Caroline M Low

David John Dunstone

Katherine Isobel Steel

Jonathan Michael Davies

Nigel Paul Shankley

Elaine Anne Harper

Robert A Hull

Michael J Bodkin

Compounds of formula (Ia), (Ib), or (Ic), wherein A represents a group having two fused rings, or a group of formula (Id), R.sup.1.sub.(m) represents up to 6 substituents, K represents --O--, --S--, --CH.sub.2 --, --N(R.sup.2)-- or --N(COR.sup.2)--, in which R.sup.2 is H or C.sub.1 to C.sub.3 alkyl, W is a carbonyl, sulfonyl or sulfinyl group, provided that at least one of W and X contains carbonyl, Y and Z are as given in the description, and their pharmaceutically acceptable salts are ligands at CCK and/or gastrin receptors. ##STR1##

Gastrin and cck receptor ligands

Gastin and CCK receptor ligands

The compounds of the formula I ##STR1## and their pharmaceutical acceptable salts, which are defined herein, are ligands for cholecystokinin and/or gastrin receptors.

Bicyclo 2,2,2!octane derivatives

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Brighton, United Kingdom

Martin Lyn Hudson