Metanomics Gmbh

Metanomics Gmbh and Co. Kgaa

Ruprecht-karls-universitat Heidelberg

Ernst-Moritz-Arndt-Universität Greifswald

Universitätsklinikum Schleswig-Holstein

Metanomics Health Gmbh

Martin Kluttig

Michael Manfred Herold

Joachim Kopka

Ralf Looser

Tilmann B Walk

Martin Dostler

Britta Lehmann

Achim Fegert

Annette Hennig

Hugo Katus

Jens Fuhrmann

Beate Kamlage

Silke Heidemann

Regina Reszka

Bianca Bethan

Holger Kalthoff

Norbert Frey

Jürgen Kastler

Tanja Weis

Johanna Wolf

Nicole Christiansen

Jörn Quedenau

Bodo Schniewind

Silke Klein

Julia Mayerle

Markus Lerch

Johanna Sigl Geb Wolf

The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject and a method for monitoring progression or regression of heart failure in a subject. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.

Means and methods for diagnosing and monitoring heart failure in a subject

The present invention relates to a process for extracting constituents from organic material, comprising the step of extracting with a monophasic mixture of 50% by volume to 90% by volume of methanol and 50 to 10% by volume of water and optionally 0% by volume to 40% by volume of a further solvent or solvent mixture.

Process for extracting constituents from organic material

The present invention relates to a process for isolating constituents from organic material, comprising the following process steps:

Method for extraction and analysis of contents made from organic material

Method for the extraction of components made from organic material

The invention relates to a method and device for analyzing a sample containing a number of substances. The method comprises the following steps: recording one or more mass spectra (mass spectra data D) of the sample (P); deconvoluting the mass spectra in a first evaluating device (A), which assigns the chromatographic peaks (a) and their associated deconvoluted mass spectra of one substance at a time based on the correspondence with a reference spectrum of the substance, and/or determining the intensity of the obtained peaks of the ions of the mass spectra in an evaluating device (B), which assigns the chromatographic peaks (b) of the ions and their associated mass spectra based on the correspondence of selective ions and their retention time ranges of the peaks (b) with the reference values of the substance predetermined for a substance, and verifying the assignments in a validating device (V).

Mass spectrometry analysis method and system

The invention relates to a method for the extraction of components made from organic material, comprising the step of extraction with a single-phase mixture of 50 to 90 vol. % methanol and 50 to 10 vol. % water and optionally 0 to 40 vol. % of a further solvent or solvent mixture.

Method for the extraction and analysis of contents made from organic material

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Berlin, Germany

Martin Kluttig