General Electric Company

Global Life Sciences Solutions USA LLC

Martin James Brown

Anup Sood

Reginald Donovan Smith

Vandana Keskar

Evelina Roxana Loghin

Ernest William Kovacs

Chrystal Mae Chadwick

Padmaparna Chadhuri

Padmaparna Chaudhuri

Provided herein are methods of activating immune cells. The method includes providing a population of immune cells and contacting the population of immune cells with a first agent and a second agent. The first agent includes an immune cell activator attached to a first binder moiety, and the second agent includes at least one capture oligomer. The at least one capture oligomer is capable of associating with the first binder moiety. Also provided are kits for activating immune cells.

Methods and kits for cell activation

Provided are methods and kits for activating T cells, the method comprising providing a population of T cells, adding a plurality of first agents, where the first agent comprises a T-cell activator and a first binder moiety, and adding a second agent comprising a plurality of capture oligomers, where at least a segment of at least one of the plurality of capture oligomers is capable of associating with the first binder moiety. The method further comprises incubating the population of T cells, whereby at least a portion of the population of T cells is activated.

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Ballston Spa, NY, United States of America

Martin James Brown