Rohm and Haas Company

Martin J Deetz

John Joseph Maikner

Jiun-Chen Wu

William Joseph Zabrodski

Biwang Jiang

The present invention further is directed to the process for making a macroporous polymeric media with covalently bonded quaternary ammonium polymer chains. The media can be applied for chromatographic purification, resulting in porous substrates having improved protein binding capacity and resin selectivity, as well as methods relating to making and using the same.

Process for making improved chromatography media and method of use

There is provided a method for making swellable particles, said method comprising mixing initial particles, at least one monomer, at least one initiator, and at least one chain-transfer agent, wherein said mixing is performed under conditions in which said monomer is capable of forming oligomer or polymer or a mixture thereof. Also provided are swellable particles made by that method. Further provided is a method of making polymeric resin particles comprising mixing at least one subsequent monomer to those swellable particles and polymerizing said subsequent monomer.

Swellable particles

A process for making substantially uniform oligomeric droplets in an aqueous dispersion comprising preparing an aqueous emulsion of an emulsifying agent, at least one monomer, a chain transfer agent, and an initiator; and mixing the aqueous emulsion with a stabilizer and a plurality of seed particles.

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North Wales, PA, United States of America

Martin J Deetz