Boehringer Ingelheim International Gmbh

Bayer Aktiengesellschaft

Bayer Intellectual Property Gmbh

Bayer Healthcare Aktiengesellschaft

Aicuris Gmbh + Co. Kg.

Bayer Schering Pharma Ag

Other

Martin Hendrix

Christina Erb

Marja Van Kampen

Adrian Tersteegen

Frank-Gerhard Böβ

Joachim Luithle

Christoph Methfessel

Dagmar Karthaus

Heike Heckroth

Rudy Schreiber

Welf-Burkhard Wiese

Karl-Heinz Schlemmer

Lars Bärfacker

Franz-Josef Van Der Staay

Frank-Thorsten Hafner

Nils Burkhardt

Frank-Gerhard Böss

Dagmar Schauss

Kerstin Henninger

Joachim Krüger

Frank Wunder

Holger Zimmermann

Gerald Kleymann

Wolfgang Bender

Timo Fleβner

Ulrich Betz

Martin Radtke

David Brueckner

Hilmar Bischoff

Dieter Lang

Riccardo Giovannini

Ulrich Rosentreter

Niklas Heine

Jörg Keldenich

Gerhard Schaenzle

Udo Schneider

Joerg Keldenich

Christian Eickmeier

Cornelia Dorner-Ciossek

Judith Baumeister

Klaus Fuchs

Dennis Fiegen

Olaf Weber

Cristina Alonso-Alija

Mary F Fitzgerald

Thomas Fox

Holger Rosenbrock

Nigel J Cuthbert

Arno Friedl

Peter Eckenberg

Volker Geiss

Maria Niewöhner, Legal Representative

Maria Niewöhner

Gerhard König

Irene Gerlach

Axel Jensen

Gabriele Handke

Volker Hinz

David Brückner

Heike Gielen

Frank-Gerhard Boess

Rüdiger Fischer

Rolf Grosser

Ruediger Fischer

Paul Naab

Ulrich Ebert

Marcus Bauser

Frank Mauler

Ulrich Niew&ouml;hner

Dietmar Flubacher

Jens-Kerim Ergüden

J&ouml;rg Keldenich

Graham Sturton

Timo Flessner

Toshiya Moriwaki

Daniela Paulsen

Reinhard Jork

Dirk Heimbach

Guy Hewlett

Ulrich Niewöhner

Armin Kern

Jürgen Stoltefuss

Maria Theresia Niewohner, Legal Representative

R&uuml;diger Fischer

Özkan Yalkinoglu

Bettina Beyreuther

Martin Michels

Tobias Laich

Yan-Hong Liu

Frank-Gerhard Böß

Richard Graham Sturton

Thorsten Oliver Repp

Frank-Gerhard B&ouml;ss

Gerhard K&ouml;nig

Lukas Goossen

Christine Erb

Welf Burkhard Wiese

The invention relates to novel heteroaryl carboxamides, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.

Heteroaryl carboxamides

The invention relates to novel heteroaryl carboxamides, a process for their preparation, and pharmaceutical compositions containing them. These materials are useful for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.

The invention relates to novel cycloalkyl- or cycloalkenyl-substituted pyrazolopyrimidinones of formula (I). wherein A, R-Rand x are as defined herein, and their use as medicaments for improving perception, concentration, learning and/or memory in patients in need thereof.

Compounds for the treatment of CNS disorders

The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory.

Selective phosphodiesterase 9A inhibitors as medicaments for improving cognitive processes

The invention relates to novel 2-heteroarylcarboxamides, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.

2-heteroarylcarboxylic acid amides

The invention relates to 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation, and their use for producing medicaments for improving learning and/or memory. The 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines are of the formula (I): with the variables as defined in the claims.

6-cyclylmethyl-and 6-alkylmethyl-substituted pyrazolepyrimidines

The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.

6-arylmethyl substituted pyrazolo[3,4-d]pyrimidines

The invention relates to alkyl-substituted pyrazolopyrimidines, process for their preparation, and the use thereof for producing medicaments for improving learning and/or memory. The alkyl-substituted pyrazolopyrimidines are of the formula (I): with the variables as defined in the claims.

Alkyl-substituted pyrazolopyrimidines

The invention relates to novel substituted pyrazolopyrimidines. Chemically, the compounds are characterized by general Formula (I): with Rbeing phenyl or pyridyl, any of which is substituted with 1 to 4, preferably 1 to 3 substituents X; X independently of each other being selected from C-C-alkyor Ci-C-alkoxy, where C-C-alkyl and C-C-alkoxy are at least dihalogenated up to perhalogenated. preferably with 2 to 6 halogen substituents, and the halogen atoms being selected from the group of fluoro, chloro and bromo, preferably fluoro; Rbeing phenyl or heteroaryl, where phenyl is substituted by 1 to 3 radicals and heteroaryl is optionally substituted by 1 to 3 radicals in each case independently of one another selected from the group of C-C-alkyl, C-C-alkoxy, hydroxycarbonyl, cyano, trifluoromethyl, amino, nitro, hydroxy, C-C-alkylamino, halogen, C-C-arylcarbonylamino, C-C-alkylcarbonylamino, C-C-alkylaminocarbonyl. C-C-alkoxycarbonyl, C-C-arylaminocarbonyl, heteroarylaminocarbonyl. heteroarylcarbonylamino, C-C-alkylsulphonyl-amino, C-C-alkylsulphonyl and C-C-alkylthio; The new compounds shall be used for the manufacture of medicaments, in particular medicaments for improving, perception, concentration, learning and/or memory in patients in need thereof. 

1, 5-dihydro-pyrazolo (3, 4-D) pyrimidin-4-one derivatives and their use as PDE9A mudulators for the treatment of CNS disorders

The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory. The pyrazolopyrimidine compounds are within the formula (I) 

The invention relates to novel cyanopyrimidinones, process for their preparation, and the use thereof for producing medicaments for improving perception, concentration, learning and/or memory.

Cyanopyrimidinones

The invention relates to heterocyclylamide-substituted thiazoles, pyrroles and thiophenes and processes for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.

Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes

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Odenthal, Germany

Martin Hendrix