Sonosep Biotech Inc.

Leybold Aktiengesellschaft

Leybold-heraeus Gmbh

Martin Groschl

Ewald Benes

Felix Trampler

Wolfgang Burger

Gernot Thorn

Friedrich-Werner Thomas

Hans-Joachim Siegmund

Gerd Pfersmann

Michael Schmid

Particulate material suspended in a fluid is separated and recycled by means of an ultrasonic resonance wave. In a preferred embodiment, the ultrasonic resonance field is generated within a multilayered composite resonator system including a transducer, the suspension and a mirror parallel to each other. Dimensions and frequencies resonant to the whole system but not exciting Eigen-frequencies of transducer and mirror itself are chosen so that thermal dissipation is minimized. Generally, the process is suitable for all kinds of particles (solid, liquid or gaseous disperse phases) especially for hydrosols (particles in water) and for separation of biological particles such as mammalian, bacterial and plant cells or aggregates. Specialized applications in biotechnology are described including an acoustic filter for mammalian cell bioreactors or the selective retention of viable cells relative to nonviable cells.

Multilayered piezoelectric resonator for the separation of suspended

Particulate material suspended in a fluid is separated and recycled by means of an ultrasonic resonance wave. In a preferred embodiment, the ultrasonic resonance field is generated within a multilayered composite resonator system including a transducer, the suspension and a mirror parallel to each other. Dimensions and frequencies resonant to the whole system but not exciting Eigen-frequencies of transducer and mirror itself are chosen so that thermal dissipation is minimized. Generally, the process is suitable for all kinds of particles (solid, liquid or gaseous disperse phases) especially for hydrosols (particles in water) and for separation of biological particles such as mammalian, bacterial and plant cells or aggregates. Specialized applications in biotechnology are described including an acoustic filter for mammalian cell bioreactors or the selective retention of viable cells relative to non-viable cells.

The invention relates to a device for recognizing the impact site (29, 37) of a charge carrier beam on a target. This device has two position-sensitive detectors (22, 23) above the target which have a given distance from each other and from the target and on which via imaging systems (24, 25) the impact site (29, 37) of the charge carrier beam is imaged by means of X-rays. The output signals of these detectors (22, 23) are placed on a special evaluation device which determines all three spatial coordinates of the impact site (29, 37) of the charge carrier beam.

Device for recognizing the impact site of a charge carrier beam on a

The invention relates to a circuit arrangement for a position sensitive radiation detector which produces a current or voltage signal (U.sub.Y) that depends exclusively on the coordinates x and y of the point of incidence of electromagnetic radiation on the EMR sensitive surface of a lateral diode (1). For this purpose, the circuit arrangement has integrators (4, 5), in which the voltages (U.sub.1, U.sub.2) are formed, which are proportional to the integral over time of the output currents (I.sub.1, I.sub.2) of the lateral diode (1). The difference between the voltages (U.sub.1, U.sub.2) is used as a signal, which depends exclusively on the coordinates at that particular time, at which the arithmetic mean of these voltages (U.sub.1, U.sub.2) has reached a preselected, constant value.

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Vienna, Austria

Martin Groschl