Hoechst Aktiengesellschaft

Aventis Pharma Deutschland, Gmbh

Sanofi-a Ventis Deutschland Gmbh

Martin Bickel

Gerhard Jaehne

Matthias Gossel

Volker Krone

Hans-Jochen Lang

Stephan Henke

Karl Geisen

Georg Tschank

Klaus Weidmann

Dietrich Brocks

Ekkehard Baader

Volkmar Gunzler

Hartmut Hanauske-Abel

Gerhard J&auml;hne

Karl-Heinz Baringhaus

Harald Burghard

Volkmar Gunzler-Pukall

Jurgen Mohr

Volkmar G unzler-Pukall

Heiner Glombik

Klaus Wirth

Heinrich Christian Englert

Rolf Geiger

Hans Jochen Lang

Max Hropot

Gerrit Schubert

Heinz-Werner Kleemann

Jochen Knolle

Bernward Scholkens

Hubert Heuer

Volker Teetz

Gerhard Beck

Gerhard Breipohl

Wilhelm Bartmann

Armin Hofmeister

Bansi Lal

Ulrich Lerch

Holger Heitsch

Eugen Falk

Dieter Mania

Oliver Plettenburg

Jurgen Blumbach

Adalbert Wagner

Volker Hitzel

Hans-Willi Jansen

Richard H Rupp

Swati Bal-Tembe

Hans G Alpermann

Harm Brummerhop

Stefan Theis

Walter Petri

Gerhard Rackur

Richard Leeb

Ramanujam Rajgopalan

Wendeline Frick

Matthias G Ssel

Klaus Weidman

Volkmar Gunzier

Alihussein Nomanbhai Dohadwalla, Deceased

Narayan Sudhindra Punekar

The invention relates to substituted fluoroglycoside derivatives of pyrazoles of formula (I) as further defined in the specification, to the physiologically compatible salts thereof, to a method for their production, and to their use as antidiabetics. 

Fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof

Embodiments of the invention relate to methods of reducing weight in mammals and for the prophylaxis or treatment of obesity comprising administration of C2-substituted indan-1-ol systems and their physiologically acceptable salts and physiologically functional derivatives. Compounds for use in the methods of the embodiments of the invention include compounds of the formula (I) in which the radicals are as defined, and their physiologically acceptable salts.

Use of C2-substituted indan-1-ol systems for preparing medicaments for the prophylaxis or treatment of obesity

The present invention is directed C2-disubstituted indan-1-ones of the Formula I, physiologically acceptable salts, and physiologically functional derivatives thereof, and pharmaceutical compositions comprising such compounds, salts and derivatives, which are useful for reducing weight, for the prophylaxis or treatment of obesity, and for the prophylaxis or treatment of type II diabetes in mammals. The invention is directed also to methods for reducing weight and such treatments and prophylaxis. The invention is directed also to processes for the preparation of such compounds.

C2-disubstituted indan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals

Embodiments of the invention relate to C2-substituted indan-1-ols and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention may include compounds of formula I in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable, for example, for use as anorectics.

C2-substituted idan-1-ols and their derivatives, processes for their preparation and their use as pharmaceuticals

Embodiments of the invention relate to C2-substituted indan-1-ols and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention may include compounds of formula Iin which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable, for example, for use as anorectics.

C2-substituted indan-1-ols and their derivatives, processes for their preparation and their use as pharmaceuticals

The present invention is directed to C2-disubstituted indan-1-ol systems of the Formula I,physiologically acceptable salts and physiologically functional derivatives thereof, and pharmaceutical compositions comprising such compounds, salts, and derivatives, which are useful for reducing weight, for the prophylaxis or treatment of obesity, and for the prophylaxis or treatment of type II diabetes in mammals. The invention is directed also to methods for reducing weight and such treatments and prophylaxis. The invention is directed also to processes for the preparation of such compounds.

C2-disubstituted indan-1-ol compounds, their derivatives, processes for their preparation, and their use as pharmaceuticals

Embodiments of the invention relate to methods of reducing weight in mammals and for the prophylaxis or treatment of obesity comprising administration of C2-substituted indan-1-one systems and their physiologically acceptable salts and physiologically functional derivatives. Compounds for use in methods of embodiments of the invention may include compounds of the formulain which the radicals are as defined, and their physiologically acceptable salts.

Use of C2-substituted indan-1-one systems for preparing medicaments for the treatment of obesity

Derivatives of C2-substituted indan-1-ol compounds of formula I:its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of obesity are disclosed herein. Compositions comprising the same, methods for preparing the instant compounds, and methods for reducing weight in mammals and for the prophylaxis or treatment of obesity are also described.

Derivatives of C2-substituted indan-1-ol systems for the prophylaxis or treatment of obesity

Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity

C2-substituted idan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals

Derivatives of C2-substituted indan-1-ol compounds, methods for their preparation and use

Polysubstituted indan-1-ol compounds, and methods for their preparation and use

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Bad Homburg, Germany

Martin Bickel