Empirical Technologies Corporation

Caretaker Medical, LLC

Other

Martin Baruch

David W Gerdt

Charles M Adkins

Indirect, oscillometric, digital blood pressure monitoring systems and methods enabling self-calibration to obtain absolute blood pressure values using algorithmic analysis of arterial pressure pulses to establish an oscillometric profile and compensate for intervening effects on digital arterial pressure. Proper algorithmic analysis is dependent upon proper positioning and maintained engagement of a digital cuff on the digit of a user and subsequent hydraulic coupling of the cuff to the arteries within the digit.

Self-calibrating systems and methods for blood pressure wave form analysis and diagnostic support

A cuff for monitoring physiological cycles has an exterior and interior surface and securing means. The cuff consists of a body having an upper curve, a lower curve and a height (CH) therebetween. A sensor adhered with a flexible protective overlay to the interior surface is in communication with a microprocessor storage means. The microprocessor storage means can be within the cuff or separate therefrom with communication between the sensor and the storage means being wireless or through a communication member. A locking tab, having a width less than the body, extends from one side of the body. A slot retaining area extends from the body on a side opposite the locking tab and contains a slot dimensioned to receive the locking tab. A pull tab is adjacent the slot retaining area opposite the body. The pull tab shares a base with the slot retaining area and has a top line and an end width less than the width of the body. The cuff can be manufactured from a hook and loop material or have other securing methods to affix the cuff in place.

Butterfly cuff

A computer-implemented method for quantifying arterial stiffness and assigning an AS factor uses executable program on a computing device. The arterial pulse of an individual is monitored and the data received from the monitoring member transmitted to the computing device. The data received is processed by the processor, performing a pulse wave analysis. The primary systolic pulse and iliac reflection pulse are extracted from the pulse wave analysis and the time delay between the primary systolic pulse and the iliac reflection pulse determined. The time delay is used to calculate a second derivative based least in part, on the time delay. The frequency above zero components are separated from the second derivative and the area of the second derivative determined between a first primary systolic pulse and a first iliac reflection pulse. A percentage score is calculated based on the degree of arterial stiffness and input into a historical population database comparing the percentage score with the population data.

Non invasive monitoring of arterial stiffness

A system for detecting dehydration, hemorrhaging, and increases in blood volume comprising monitors the time difference between the arrival of the primary left ventricular ejection pulse (pulse T1) and the arrival of the iliac reflection (pulse T3) to determine an arterial pulse parameter which is the time difference between T1 T3. Changes in T3 minus T1 are indicative of something happening to blood volume. If the T1-3 value goes up and the patient is on an infusion system, it can be an indication of having too much fluid pumped and if T1-3 is lower than it should be for an individual, they are either dehydrated (which can result in decreases in blood volume), they are hemorrhaging, or they have hemorrhaged. A downtrend in T13 can tell whether someone is continuing to hemorrhage.

Detection of progressive central hypovolemia

Determining physiological life signs, with a sensor that is in contact with the surface of a patient's skin at point proximate an artery, and measuring arterial blood vessel displacement and/or blood pressure changes. A data stream of measurements of is collected and a set of parameters from the collected data, a number of physiological life signs parameters, is extracted from the data. The physiological life signs that can be extracted include heart rate, breathing rate, systolic blood pressure, and diastolic blood pressure.

Arterial pulse decomposition analysis for vital signs determination

Blood pressure determination with resolution sufficient to resolve Pulsus Paradoxus is based on measurement of delay time between points on a heartbeat pulse.

Blood pressure determination based on delay times between points on a heartbeat pulse

A fiberoptic sensing apparatus comprises a fiberoptic coupler in which a plurality of optical fibers are joined through a fused coupling region, the optical fibers including at least one input optical fiber and a plurality of output optical fibers, the fiberoptic coupler distributing light incident to the input optical fiber among the plurality of output optical fibers. The coupler is mounted to a support member and configured such that at least a portion of the coupling region can be deflected to change the light distribution among the output fibers without putting the coupling region under tension. A fluid column is cooperative with a deflection member disposed to deflect the portion of the coupling region.

Sensing apparatus employing variable coupler fiberoptic sensor

A variable coupler fiberoptic sensor utilizes a coupler having a fused coupling region that can be deflected to change the light distribution to a plurality of output fibers without putting the coupling region under tension. A compact, rugged, and highly sensitive sensor design is achieved by use of a coupler having a fused coupling region arranged substantially in a U-shape to allow the input and output fiberoptic leads to extend from the same side of the sensor structure.

Variable coupler fiberoptic sensor and sensing apparatus using the sensor

In a method of measuring pulse transit time of a living subject, first and second pulse wave signals are produced by sensing the pulse at first and second pulse points, respectively, the first and second pulse points being spaced from one another. The first and second pulse wave signals are differentiated, and based on the results, corresponding points of the first and second pulse wave signals are selected (e.g., points of maximum slope). The time delay between the selected points is determined, thus yielding the pulse transit time. A preferred apparatus measures pulse transit time using at least one fiberoptic pulse sensor including a fused-fiber coupling region having at least a portion that can be deflected without putting the coupling region under tension.

Apparatus and method for measuring pulse transit time

A sensing pad assembly for monitoring acoustic activity or motion of an object supported on the pad utilizes an improved fiberoptic sensor as a pressure transducing element to convert pressure fluctuations due to the acoustic activity or motion to an output that changes in accordance with the pressure fluctuations. The sensor has an improved design that permits deflection of the coupler fusion region without accompanying tension. In a preferred embodiment, the coupler fusion region is arranged substantially in a U-shape so that the fiberoptic leads of the sensor may be located adjacent to each other at one side of the sensor.

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Charlottesville, VA, United States of America

Martin Baruch