Bayer Technology Services Gmbh

Weidmann Plastics Technology Ag

Bayer Intellectual Property Gmbh

Martin Andreas Bopp

Michael Pawlak

Markus Ehrat

Gert Ludwig Duveneck

Eveline Schürmann-Mader

Andreas Peter Abel

Gerhard Matthias Kresbach

Eginhard Schick

Tilo Callenbach

Nania Graciela Schärer-Hernández

Max Gmür

Heinz Lüthi

Yves Marmier

Wolfgang Zesch

Heinrich Büttgen

André Marcel Wicky

Werner Schoch

The planar optical structure forms an evanescent-field measuring platform. A body is made from the thermoplastic plastic with a three-dimensionally structured surface, wherein molding is performed directly from a master made of glass coated with metal oxide, without deposition of further coatings on a surface of the master. The planar optical structure forming an evanescent-field measuring platform has a first essentially optically transparent, waveguiding layer (a) with a refractive index nand a second essentially optical transparent layer (b) with refractive index n, where n&#x3e;n, in a case of an embodiment of a planar optical film waveguide, or a metal layer (a') and a second layer (b), in a case of an embodiment for generating a surface plasmon resonance, wherein the second layer (b) includes a material from a group of cyclo-olefin polymers and cyclo-olefin copolymers.

Planar optical structure forming an evanescent field measuring platform that includes a layer molded by a master

A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents. An arrangement of one or more sample compartments includes a base plate and a body combined with the base plate in such a way that one or more recesses for generation of one or more flow cells fluidically sealed against one another, each with at least one inlet and one outlet, are formed between the base plate and the body, wherein at least one outlet of each flow cell is joined with a reservoir fluidically connected with the flow cell, the reservoir being operable to receive liquid exiting the flow cell, besides methods for its manufacturing and their use.

Flow cell array and the utilization thereof for multianalyte determination

The invention relates to embodiments of an optical system for luminescence determination, comprising two or more excitation light sources, a sensor platform and an optical component with several discrete facets for beam deflection towards the sensor platform. Further subjects of the invention are methods for luminescence determination with an optical system according to the invention and analytical systems, as well as the use of these methods for quantitative affinity sensing and for various other applications. The aim of the present invention is to provide optical and analytical measuring devices for highly sensitive detection of one or more analytes, using a multitude of measurement areas on a common carrier.

Multianalyte determination system and methods

The present invention relates to a method for manufacture a body from a thermoplastic plastic with a three-dimensionally structured surface, wherein molding is performed directly from a master made of glass coated with metal oxide, without deposition of further coatings on a surface of the master. The invention also relates to bodies manufactured with this method from a thermoplastic featuring a three-dimensionally structured surface, as well as to planar optical structures likewise manufactured with this method for generating evanescent-field measuring platforms and to a use thereof. The invention furthermore relates to a planar optical structure for generating an evanescent-field measuring platform, comprising a first essentially optical transparent, waveguiding layer (a) with refractive index nand a second essentially optical transparent layer (b) with refractive index n, where n&#x3e;n, in a case of an embodiment of a planar optical film waveguide, or comprising a metal layer (a') and a second layer (b), in a case of an embodiment for generating a surface plasmon resonance, wherein the second layer (b) comprises a material from a group comprising cyclo-olefin polymers and cyclo-olefin copolymers.

Method for production of moulded bodies, in particular optical structures and use thereof

The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising

Kit and method for multi-analyte determination

A system of flow-through cells is obtained by assembling a body with a base plate. The body has a first spring element and a first stop, disposed on opposite end sections of the body, at least one second spring element and a corresponding second stop, disposed on opposite faces of the body, and at least one support element and at least one retaining element, which are adapted for the exact positioning of the body in the receiving openings of a support in three directions.

Body for flow-through cells and the use thereof

Kit and method for determining a plurality of analytes

Growing community of inventors

Basel, Switzerland

Martin Andreas Bopp