Ciba-Geigy Corporation

Institut De Recherche En Ophtalmologie

Martial Geiser

Hans Peter Herzig

Alfredo E Bruno

Beat Krattiger

Benno L Petrig

Charles E Riva

An apparatus is provided for the measurement of the velocity of blood flowing within a blood vessel of an eye wherein the apparatus includes a light source for producing a source beam of light and an optical element for applying the source beam of light to the blood vessel to permit the blood flowing within the blood vessel to scatter a portion of the source beam of light and produce bidirectional scattered beams. A detector system for detecting the bidirectional scattered beams provides signals representative of the scattered beams. The light source and the detector system are disposed in a confocal relationship. An output representative of the velocity of the blood flow velocity is produced in accordance with the signals. The light source and the detector system include respective pinholes wherein the respective pinholes are disposed in the confocal relationship. The blood vessel is conjugate with the respective pinholes of the light source and the detector system. The angle between the bidirectional scattered beams is determined and a measurement of blood flow velocity is determined according to the angle.

Confocal bidirectional laser doppler velocimetry

An interferometric apparatus for monitoring changes of the refractive index of An interferometri1capillary tubes comprising a source of coherent light, which is arranged with respect to a capillary tube which is part of a capillary liquid chromatographic system or a capillary electrophoretic system, such that the coherent light beam strikes the capillary tube about perpendicular to its longitudinal extension. In the forward direction of the coherent light beam, behind the capillary tube, the apparatus comprises a photoelectric detector for monitoring a resulting interference fringe pattern and the shifts thereof, which is connected to an evaluation electronics. Between the light source and the capillary tube there is arranged a beam splitting optical element for generating a converging probe beam, which travels along a probe beam axis and strikes the capillary tube at its bore, and a converging reference beam, which travels along a reference beam axis, that extends generally parallel to the probe beam axis and is located in close vicinity to the probe beam axis, and which does not strike the capillary bore.

Interferometric apparatus for monitoring changes of the refractive index

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Sion, Switzerland

Martial Geiser