Children's Medical Center Corporation

Rhode Island Hospital

Martha M Murray

Braden C Fleming

Michael F Murray

Jennifer Marler

Alexander H Slocum

Daniel L Walker

Matthew R Carvey

Ying-Chih Wang

Alexey Salamini

Methods and devices for the repair of a torn or injured ligament or tendon are provided. The methods include the use of multiple scaffolds, e.g., beads. The multiple scaffolds may be positioned along a suture or other device such that they are moveable with respect to one another or the injured tissue.

Indirect method of articular tissue repair

Methods for preparing and using collagen extracts and collagen scaffolds are provided. Additionally methods and related kits for the repair of articular tissue using the collagen material are provided.

Collagen scaffolds

Methods for preparing and using collagen extracts and collagen scaffolds are provided. Additionally, methods and related kits for the repair of articular tissue using the collagen material are provided.

The present disclosure provides biomaterials and methods for preventing and minimizing progression of cartilage and/or connective tissue damage. Also provided herein are biomaterials and methods for alleviating and/or reducing the risk for developing arthritis (e.g., osteoarthritis) associated with joint injury and/or joint surgery.

Biomaterial for articular cartilage maintenance and treatment of arthritis

The current subject matter provides a tool for evaluating the risk of failure or the likelihood of success of surgery of healing ligaments and tendons in the body. In some embodiments, a region of a scan comprising one or more of an anterior cruciate ligament (ACL) or an ACL graft can be defined. A magnetic resonance (MR) imaging data set can be obtained. MR parameters characterizing a size and a quality of the ACL or ACL graft can be derived using the MR data. The MR parameters can be used as inputs to a predictive model. A score characterizing a likelihood of failure of the ACL or ACL graft in a human patient can be generated using the predictive model.

Non-invasive measurement to predict post-surgery anterior cruciate ligament success

Methods and devices for the repair of a ruptured ligament using a scaffold device are provided. Aspects of the invention may include a scaffold attached by a suture to an anchor. In aspects of the invention, the anchor may be secured to a bone near or at the repair site.

Methods and procedures for ligament repair

Methods and devices for the repair of a ruptured ligament using a scaffold device are provided. Aspects of the invention, may include a scaffold attached by a suture to an anchor. In aspects of the invention, the anchor may be secured to a bone near or at the repair site.

Methods and devices for the repair of a ruptured ligament using a scaffold device are provided. Aspects of the invention may include a scaffold attached by one or more sutures to one or more anchors. In aspects of the invention, the anchors may be secured to a bone near or at the repair site.

Methods and devices for the repair of articular tissue using collagen material are provided. Compositions of collagen material and related kits are also provided.

Methods and products for tissue repair

The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

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Sherborn, MA, United States of America

Martha M Murray