Schering Aktiengesellschaft

Richter Gedeon Vegyeszeti Gyar Rt

Egis Gyogyszergyar Rt.

Marta Szollosy

Ferenc Andrasi

Tamas Hamori

Pal Berzsenyi

Istvan Tarnawa

Istvan Ling

Sandor Solyom

Antal Simay

Melinda Gal

Gizella Abraham

Egon Karpati

Gyorgy Hajos

Imre Moravcsik

Bela Hegedus

Gyorgy Fekete

Katalin Csomor

Peter Tetenyi

Gabor Zolyomi

Andrea Maderspach

Istvan Pallagi

Eszter Szentkuti

Katalin Eszter Horvath

Anna Kallay Nee Sohonyai

Emese Csuzdi

Katalin Horvath

Marta Kapolnas Nee Pap

Ernese Csuzdi

Tibor Hasko

Laslo Szporny

Kalmen Harsanyi

Andres Javor

Franciska Erdo

Emese Csuzdl

Gabor Kapus

Erzsebet Birkas

Compounds of formula I are described, their production and use in pharmaceutical agents.

Condensed 2,3-benzodiazepine derivatives and their use as AMPA-receptor inhibitors

Derivatives of 2,3-benzodiazepine are substituted by one or two halogen atom(s) and have the general formula ##STR1## These derivatives are non-competitive AMPA antagonists and are used in pharmaceutical compositions. A process to make the 2,3-benzodiazepine derivatives includes converting starting compounds which are substituted by one or two halogen groups and have the general formula ##STR2##

2,3-Benzodiazepine Derivatives as non-competitive AMPA

3-substituted 3H-2, 3-benzodiazepine derivatives, the production and use

The invention relates to novel, sulfur-containing 5-substituted benzimidazole derivatives of formula I ##STR1## and acid-addition salts thereof antihyperlipoproteinemic action, a process for preparing the same, pharmaceutical formulations comprising the novel compound as active ingredient and a method for inhibiting atherosclerosis, trombus formation and treating hyperlipoproteinemic diseases.

Antihyperlipoproteinemic 5-substituted sulfur-containing benzimidazole

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Budapest, Hungary

Marta Szollosy