Almirall, S.a.

Laboratorios Almirall, S.a.

Marta Carrascal Riera

Jordi Gracia Ferrer

Joan Taltavull Moll

Juan Francisco Caturla Javaloyes

Montserrat Erra Sola

Francisco Javier Bernal Anchuela

Maria Antonia Buil Albero

Lluis Miquel Pages Santacana

Victor Giulio Matassa

Nuria Aguilar Izquierdo

Vittorio Dal Piaz

Emma Terricabras Belart

Maria Paola Giovannoni

Claudia Vergelli

Marta Mir Cepeda

Gaspar Casals Coll

Maria Begoña Hernandez Olasagarre

New pyrrolotriazinone derivatives having the chemical structure of Formula (I) are disclosed; as well as process for theft preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks). 

Pyrrolotriazinone derivatives as PI3K inhibitors

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks). 

Pyrrolotriazinone derivatives as inhibitors P13K

Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4. R, Rand Rare organic radicals, Ris a cyclic group, and Ris an ester or an aryl or heteroaryl group. 

Pyridazin-3(2H)-one derivatives

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Marta Carrascal Riera