Araceli Biosciences, Inc.

Phoseon Technology, Inc.

Nlight Photonics Corporation

Marshall Anderson

Tyler Wilson

Marguerite Vantangoli Policelli

David James Tasker

Jeffrey Alan Harris

Theresa Thompson

David Tasker

Jonathan M McGuire

Jeffrey Harris

Michael Sjaastad

Methods and systems are provided for a microscope assembly. In one example, the microscope assembly include an objective arranged at a top of a plate and aligned with a first side of the plate and a tube lens positioned below the objective along the first side of the plate and spaced away from the objective. The assembly further includes a laser auto-focus oriented parallel with a height of the plate and a light source coupled to a central region of the front face of the plate, between the tube lens and the laser auto-focus.

High throughput microscope assembly

Methods and systems are provided autofocusing an imaging system. In one example, a method includes identifying a target focal plane of a field-of-view (FOV) of each objective of the imaging system, the imaging system including two or more objectives, adjusting a vertical position of each objective relative to the target focal plane based on a light shape generated from a laser beam, and aligning a focus of each objective according to a power level detected by a sensor.

Method and systems for autofocusing

Methods and systems are provided for a sample holder for a multi-detector quantitative microscopy system. In one example, the sample holder includes a frame with a central opening, a pivotable arm positioned adjacent to the central opening and having a whippletree assembly at a first end of the pivotable arm, and a movable ram, in contact with a second end of the pivotable arm, the movable ram configured to pivot the pivotable arm.

Microplate holder for imaging system

Methods and systems are provided for an imaging system. In one example, the imaging system includes a plurality of microscope assemblies arranged radially around a central axis of the imaging system, coupled to vertically oriented plates with a set of objectives arranged at tops of the plurality of microscope assemblies and wherein the plates are oriented to extend away from the central axis in a radial direction to form an x-shaped configuration.

High throughput quantitative microscopy system

Methods and systems are provided for synchronizing image capture at a multi-detector imaging system. In one example, a method includes coordinating cycling of each microscope assembly of the multi-detector imaging system through a selection of illumination channels, each microscope assembly configured to obtain an image of a portion of one of more than one microplate wells simultaneously, to generate complete images of the more than one microplate wells concurrently.

Light synchronization for an imaging system

Methods and systems are provided for photochemically synthesizing tetrachloromethane in an industrial scale using a plurality of arrays or channels of light emitting diodes. A wavelength output by an SLM lamp is customized to bias the photochemical reaction towards a target reaction and target product and away from a side reaction and side product. The higher yield of the target product improved efficiency and reduces the need for complex purification for removal of the side product.

Method and system for tetrachloromethane synthesis

A resonator mounting assembly includes a resonator cage, a base underlying the resonator cage, a plurality of first sets of kinematic mounting elements with the kinematic mounting elements of each first set mated with one another in an engaged non-secured relationship so as to support the resonator cage above the base and provide a kinematic mounting interface between them that substantially prevents any rotational moments applied on the base to be transferred to the resonator cage, and at least one second set of preload mounting elements fastened with one another in a yieldable secured relationship so as to preload the resonator cage relative to the base to maintain a positive contact at the kinematic mounting interface that substantially prevents disengagement of the mated kinematic mounting elements from one another due to forces and moments generated from thermal expansion and mounting distortion of the base.

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Portland, OR, United States of America

Marshall Anderson