Autonomous Medical Devices Inc.

Marlon S Thomas

Yehoshua Shachar

Stelica Stelea

Josh Shachar

Marc Rocklinger

Peter Yin

Sam Gurley

Rob Purnell

Aaron Cipriano

Ming Petrullo

The illustrated embodiments include a method of operating a SAW sensor to detect a sample in a fluid which includes the steps of: providing a SAW sensor with a functionalized detection lane in a handheld, portable assay device and sensor system; maintaining the functionalized detection lane of the SAW sensor dry until the sample is fluidically disposed in the detection lane; fluidically disposing the sample in the functionalized detection lane; removing fluid the functionalized detection lane to concentrate the sample in the functionalized detection lane to increase the probability of a specific antibody-antigen interaction; washing the functionalized detection lane so that substantially only the specific antigen-antibody interaction remains in the functionalized detection lane; removing fluid from the functionalized detection lane again; and measuring concentration of the sample while the functionalized detection lane is fluid-free.

Detection of cardiac troponin or biological markers via shear horizontal surface acoustic wave biosensor using a wet-dry bioanalytical technique

An cartridge is combined with a smart device which is capable of communicating with a network to perform a portable, fast, field assay of a small sample biological analyte. A closed microfluidic circuit for mixes the analyte with a buffer with functionalized magnetic beads capable of being specifically combined with the analyte. A detector communicates with the microfluidic circuit in which the mixed analyte, buffer and combined functionalized magnetic beads are sensed. A microcontroller is coupled to detector for controlling the detector and for data processing an output assay signal from the detector. A user interface communicates with the microcontroller for providing user input and for providing user output through the smart device to the network.

Apparatus for automatic sampling of biological species employing an amplification with a magnetic nanoparticle and propulsion method

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Riverside, CA, United States of America

Marlon S Thomas