Evolva Sa

Ajinomoto Co., Ltd.

Roquette Freres

Basf Se Corporation

Markus Schwab

Anaelle Hatsch

Sophie Defretin

Yiming Chang

Friederike Thor

Arnaud Heysen

Tania Gerard

Sumire Honda Malca

Melanie Diefenbacher

Astrid Schaefer

Sabina De Andrade Pereira Tavares

David Fischer

Maud Babau

Corina Daniela Wirdnam

Oskar Zelder

Klaus Ditrich

Karsten Koerber

Michael Breuer

Stefan Haefner

Holger Hartmann

Hartwig Schroeder

Michael Naesby

Birgit Hoff

Christophe Folly

Fanny Delegrange

Thomas Oestergaard Tange

Curt Aimé Friis Nielsen

Andrea Molt

Jens Klein

A method for producing an objective substance such as sphingoid bases and sphingolipids using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing an additive that is able to associate with, bind to, solubilize, and/or capture the objective substance, and collecting the objective substance from cells of the yeast and/or the culture medium.

Method for producing sphingoid base or sphingolipid

A method for producing an objective substance such as phytosphingosine and sphinganine using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so that the expression and/or activities of proteins encoded by LCB4 and CKA2 genes are reduced in a culture medium, and collecting the objective substance from cells of the yeast and/or the culture medium.

Method for producing phytosphingosine or sphinganine

The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding a NAD-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding a NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.

Production of xylitol from glucose by a recombinant strain

The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding an NAD+-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding an NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.

Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.

Genes and processes for the production of clavine-type alkaloids

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Loerrach, Germany

Markus Schwab