Evonik Degussa Gmbh

Evonik Rohm Gmbh

Markus Pötter

Thomas Haas

Steffen Schaffer

Jan Christoph Pfeffer

Arne Skerra

Martin Roos

Hans-Georg Joerg Hennemann

Wolfgang Kroutil

Thomas Tacke

Mirja Wessel

Hermann Siegert

Stefan Buchholz

Harald Häger

Daniel Demicoli

Andreas Schmid

Liv Reinecke

Frank Erhardt

Bruno Bühler

Alexandra Lerchner

Eva-Maria Eckl

Jasmin Corthals

Marie-Dominique Przybylski-Freund

Andreas Pfennig

Anja Schubert

Johann H Sattler

Sjef Cornelissen

Manfred Schrewe

Mattijs Kamiel Julsing

Birgit Alber

Katharina Christin Tauber

Silvana Roeder

Achim Marx

Marie-Dominique Przybylski

Georg Fuchs

The present application relates to a process for removing an organic compound having one or more positive charges from an aqueous solution, comprising the steps a) provision of the aqueous solution comprising the organic compound and of a hydrophobic organic solution which comprises a liquid cation exchanger, where the liquid cation exchanger is hydrophobic, and where the liquid cation exchanger has one or more negative charges and an overall negative charge, b) contacting the aqueous solution and the organic solution, and c) separating off the organic solution from the aqueous solution.

Liquid cation exchanger

A process for producing alanine, including culturing a cell under aerobic conditions in an aqueous phase in the presence of an inorganic nitrogen source, and then contacting the aqueous phase and the cell cultured in the aqueous phase with a hydrophobic organic phase. The cell is a prokaryotic or a lower eukaryotic cell and expresses a recombinant alanine dehydrogenase.

Method for aerobically producing alanine or a compound produced using alanine

A method including the steps a) providing a primary alcohol of the formula HO&#x2014;(CH)&#x2014;R, where Ris &#x2014;OH, &#x2014;SH, &#x2014;NHor &#x2014;COOR; x is at least 3; and Ris H, alkyl or aryl, b) oxidizing the primary alcohol by contacting it with an NAD(P)-dependent alcohol dehydrogenase, and c) contacting the oxidation product of step a) with a transaminase, where the NAD(P)-alcohol dehydrogenase and/or the transaminase is a recombinant or isolated enzyme. A whole cell catalyst for carrying out the method. The use of such a whole cell catalyst for oxidizing a primary alcohol.

Oxidation and amination of primary alcohols

The invention provides a biocatalytic process for oxidation of organic compounds with the aid of an alkL gene product, and microorganisms used in this process.

Biocatalytic oxidation process with AlkL gene product

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Münster, Germany

Markus Pötter