Evonik Degussa Gmbh

Evonik Operations Gmbh

Evonik Roehm Gmbh

Markus Poetter

Thomas Haas

Steffen Schaffer

Hans-Georg Joerg Hennemann

Frank Erhardt

Harald Haeger

Martin Roos

Achim Marx

Oliver Thum

Jan Christoph Pfeffer

Lothar Eggeling

Takuya Matsumoto

Thomas Tacke

Mirja Wessel

Hermann Siegert

Alexander May

Stefan Buchholz

Daniel Demicoli

Liv Reinecke

Christian Gehring

Bruno Buehler

Ralf Kelle

Philip Engel

Anja Schubert

Andreas Pfennig

Marie-Dominique Przybylski-Freund

Sabine Hafkemeyer

Jasmin Gielen

Dong Cao

Lukas Falke

Katharina Berse

Marion Schiebelhut

Birgit Alber

Guoqing Tao

Georg Fuchs

Mattijs Kamiel Julsing

Sjef Cornelissen

Andreas Schmid

Manfred Schrewe

A method for oxidizing an alkyl, including a) contacting the alkyl with an aqueous solution comprising a microorganism where the microorganism has a reduced fatty acid degradation capacity compared to its wild type, wherein the fatty acid degradation capacity is reduced by deletion, inhibition or inactivation of a gene encoding an enzyme involved in the &#x3b2;-oxidation pathway; and the microorganism expresses a recombinant alkane oxidase, and b) contacting the aqueous solution from a) with a water-immiscible organic solvent.

Biotechnological production of alcohols and derivatives thereof

Provided is a method of producing at least one omega-hydroxyl fatty acid, the method comprising: (a) contacting at least one alkane with at least one recombinant yeast cell in an aqueous medium, wherein the yeast cell is capable of oxidising the alkane to the corresponding omega-hydroxyl fatty acid and the yeast cell comprises a reduced fatty acid degradation capacity.

Process of producing omega-hydroxyl fatty acid from alkane

The invention relates to a cell which has been genetically modified so as to be capable of producing more 2-hydroxyisobutyric acid or more polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units than its wild type, characterized in that 2-hydroxyisobutyric acid or polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units are produced via acetoacetyl-coenzyme A as intermediate and 3-hydroxybutyryl-coenzyme A as precursor.

Recombinant cell producing 2-hydroxyisobutyric acid

The present invention relates to a method for removing an organic compound from an aqueous solution, comprising the steps of providing the aqueous solution which contains the organic compound, and a hydrophobic organic solution, where the latter comprises a liquid hydrophobic cation exchanger, contacting the aqueous solution and the hydrophobic organic solution, and separating off the hydrophobic organic solution from the aqueous solution, wherein the liquid hydrophobic cation exchanger is a saturated alkanoic acid having at least one alkyl substituent, where the organic compound is an organic compound having at least one positive charge and a neutral or positive total charge.

Branched-chain fatty acids as liquid cation exchangers

The invention relates to a method for removing an organic compound having one or more positive charges from an aqueous solution. Said method consists of the following steps a) the aqueous solution containing the organic compound, and a hydrophobic organic solution which contains a hydrophobic liquid cation exchanger having one or more negative charges and a negative total charge, are provided, b) the aqueous solution and the organic solution are brought into contact with each other and c) the organic solution is separated from the aqueous solution.

Liquid cation exchanger

A process for the improved separation of a hydrophobic organic solution from an aqueous culture medium is provided. The process includes preparing an aqueous culture medium of a metabolically active cell having a decreased activity; contacting of the aqueous culture medium with a hydrophobic organic solution comprising a substrate for biotransformation; conducting a biotransformation of the substrate; and separating the hydrophobic organic solution comprising a biotransformed substrate from the aqueous culture medium. The decreased activity of the metabolically active cell is in comparison to a wild-type of the active cell and the decreased activity is of at least of one enzyme that catalyzes one reaction of &#x3b2;-oxidation of fatty acids. The invention further provides a metabolically active cell that has a decreased activity, compared to its wild-type, of an enzyme that catalyzes one of the reactions of the &#x3b2;-oxidation of fatty acids, including an enzyme selected from FadA, FadB, FadD, FadL and FadE as well as variants thereof.

Process for the improved separation of a hydrophobic organic solution from an aqueous culture medium

The present invention relates to a process for the preparation of methacrylic acid or methacrylic esters, comprising the process steps of The invention also relates to a process for the preparation of polymethacrylic acid or polymethacrylic esters.

Process for preparing methacrylic acid or methacrylic esters

The invention relates to genetically engineeredcells, use thereof and a method of production of &#x3c9;-hydroxycarboxylic acids and &#x3c9;-hydroxycarboxylic acid esters.

[object Object]

Growing community of inventors

Muenster, Germany

Markus Poetter