Dsm IP Assets B.v.

Roche Vitamins Inc.

Markus Nowotny

Raphael Beumer

Bruno H Leuenberger

Chyi-Cheng Chen

Jean-Claude Tritsch

Christian Schaefer

Markus Beck

Bernd Schlegel

Concetta Tedeschi

Juergen H Vollhardt

Jochen Weiss

Philippe Emmanuel Maillan

Heinz Gutzwiller

Anne Kessler

Zdravka Misic

Christiane Maier

Guido Schaer

Karl Manfred Voelker

Hansjoerg Grass

Antihypertensive agents which are crystalline having a general plate shape may be difficult to formulate as they often do not exhibit good flowability properties. Addition of spray-dried riboflavin surprisingly improves flowability of these agents.

Medicaments containing riboflavin exhibiting improved flowability

The present invention relates to new (foodgrade) solid lipid nanoparticles, as well as the production of such solid lipid nanoparticles and the use of them.

Solid lipid nanoparticles (II)

The present invention is directed to topical compositions, comprising isoflavone nanoparticle compositions. The isoflavone nanoparticle compositions contain isoflavone in the form of nanoparticles and preferably a carrier. In the topical compositions recrystallization of the isoflavone to bigger particles is avoided.

Topical compositions comprising nanoparticles of an isoflavone

The invention is concerned with a novel process for the manufacture of flowable, non-dusty, binder-free riboflavin granulates by subjecting an aqueous suspension of riboflavin crystals of crystal modification B/C to a fluidized bed spray drying process, a single fluid nozzle spray drying process or a disk-type spray drying process.

Process for preparing spray granules containing riboflavin

Method and device for atomizing liquids

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Basel, Switzerland

Markus Nowotny