Basf Se Corporation

Basf Aktiengesellschaft

Markus Nett

Michael Rack

Jan Klaas Lohmann

Hubert Sauter

Michael Keil

Thomas Grote

Herbert Bayer

Thomas Zierke

Bernd Mueller

Horst Wingert

Ruth Muller

Jochen Dietz

Ana Escribano Cuesta

Heinz Isak

Sebastian Peer Smidt

Remy Benoit

Michael Seet

Georg Christoph Rudolf

Rainer Hoffmann

Preparation of optionally substituted dihydroisoquinolines. The present invention relates to a process for the preparation of optionally substituted dihydroi-soquinolines of the formula I.

Preparation of optionally substituted dihydroisoquinolines

The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which Ris H, halogen, nitro, C-C-alkyl, C-C-haloalkyl, C-C-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, &#x2014;C(&#x2550;O)&#x2014;OR, &#x2014;C(&#x2550;O)&#x2014;NRR, &#x2014;C(&#x2550;O)&#x2014;SRor &#x2014;C(&#x2550;S)&#x2014;SR; Ris H, C-C-alkyl, benzyl or phenyl; Ris H, halogen, C-C-alkoxy, C-C-haloalkoxy, C-C-cycloalkoxy, C-C-alkenyloxy, C-C-alkylthio, C-C-haloalkylthio, C-C-cyclo-alkylthio or C-C-alkenylthio; compounds of the formula (II.a) or (II.b), in which Rand Reach have one of the definitions given above; Ris halogen, &#x2014;OR, &#x2014;SR, &#x2014;O&#x2014;SO&#x2014;Ror an &#x2014;NRRgroup; Rand Rare each C-C-alkyl, C-C-haloalkyl, C-C-cycloalkyl, benzyl or phenyl, or, together with the nitrogen atom to which they are bonded, are a 3- to 8-membered heterocycle; Lewis acid adducts of compounds of the formula (II.b); the use of compounds of the formula (II.a) or (II.b) and of the Lewis acid adducts for preparing compounds of the formula (I) or (VI);and to a process for converting such compounds to the corresponding 3-difluoro-pyrazol-4-ylcarboxylic acids.

Method for producing difluoromethyl-substituted pyrazole compounds

A process and intermediates for preparing .alpha.-methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: ##STR1##

Preparation of a-methoxyiminocarboxylic acid methylamides and

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Schifferstadt, Germany

Markus Nett