Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

The Rockefeller University

Markus Kalkum

Holger Eickhoff

Brian T Chait

Andrew N Krutchinsky

Herbert Cohen

Vadim Sherman

Markus Kietzmann

Holger Rauth

Richard Reinhardt

Martin M&uuml;ller

Eckhard Nordhoff

Martin Müller

Martin Horn

Eckhardt Nordhoff

Rudolf Germer

Christine Gauss

Carsten Arold

Thomas Przewieslik

A system for determining the ratio of mass to charge of an ion including a pulsed ionizer, a high pressure co-linear ion guide/accelerator, and a mass analyzer. The pulsed ionizer generates intact analyte ions from a sample of matter to be analyzed. The high pressure co-linear ion guide/accelerator is interfaced with the ion source for receipt of the intact ions of the sample. The ion guide/accelerator simultaneously dampens and linearly accelerates the intact ions in the substantial absence of fragmentation of the ions to provide a substantially continuous beam of the intact ions for mass analysis. The mass analyzer is connected to the ion guide/accelerator for receipt of the beam of ions and determines the mass to charge ratio of the intact ions.

Method and system for mass spectroscopy

For processing of substances in the reservoir () of a microdroplet dosing device (), movement of a solid carrier material with a binding-active surface takes place in the reservoir, and binding of the substance takes place on the surface of the carrier material which comprises magnetic particles () or a carrier pad.

Method and device for processing extremely small substance quantities

A sample taking apparatus comprises a plurality of separation tools () (for example, punching capillaries) on a holding device (), wherein the separation tools () are each provided with actuating means () for separate control thereof. In a sample taking method (for example, for punching samples from separation gels), successively removed samples are deposited in parallel onto a target substrate.

Apparatus and method for taking samples from polymer support material

The invention relates to a process for the isolation and/or purification of a proteinaceous material, wherein a solid phase comprising a mixture of hydrophobic and hydrophilic groups is used.

Process for the isolation and/or purification of a proteinaceous material

Method of transmitting ions for mass spectroscopy

A multi-channel dispensing head including a plurality of micropipettes, each micropipette having an electrically actuatable trigger device with a ground and signal terminal; and a shared carrier having a plurality of receptacles located in a one- or two-dimensional arrangement and sized and shaped to receive said micropipettes, each receptacle having a ground and signal contact, wherein the ground and signal contacts on the carrier are spaced apart in the direction of a longitudinal axis extending through the respective micropipettes and each of the ground and signal contacts on the carrier contacting the ground and signal terminals of the trigger devices, respectively.

Device and procedure for the electrically triggered microdrop release with a dispensing head

A procedure for detecting microparticles released by at least one dispenser, encompassing the following steps: (a) triggering the dispenser over an oscillation target ( ) with a sensor material ( ), so that at least one microparticle hits the sensor material ( ) and excites an acoustic wave, (b) detecting the acoustic wave with at least one oscillation sensor ( ) connected with the sensor material ( ), which emits an electrical sensor signal when the acoustic wave arrives, and (c) evaluating the sensor signal to determine the impact of the microparticle. The procedure is aimed at detecting the impact and/or impact positions of microparticles on a target. A detector for executing the procedure is also described.

Procedure and device for acoustically detecting microparticles

For the detection of the position and/or velocity of microparticles which move from dispensers of a dispensing head ( ) to a target, a detector target with two linear bound, electro-acoustic or electro-optic interactive areas which fix a target plane is used. When microparticles impact on the interactive areas, detector signals are determined from which along with the dispensing head position motion parameters of the microparticles are obtained.

Process and device for detecting microparticle movement

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New York, NY, United States of America

Markus Kalkum