Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt

Gsf-forschungszentrum Fur Umwelt Und Gesundheit, Gmbh

Tecniplast S.p.a.

Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt Gmbh

Markus Brielmeier

Carmelo Di Martino

Gianpaolo Milite

J&ouml;rg Schmidt

Julia Zorn

Wolfgang Nagel

Alfredo Campiotti, Ii

Jörg Schmidt

Joerg Schmidt

Jorg Schmidt

The present invention concerns a device for improved hygienic monitoring of individually ventilated caging (IVC) rack systems for laboratory animals and method for contamination-free removal of biological samples from unwanted organisms from the IVC-rack system. The device allows the performance of sampling operations on a ventilated shelving system in a safe and effective manner, without interfering with the ventilation air flow. The method of the invention allows the removal and transfer of the biological sample from inside the IVC-rack in a contamination-free manner by enabling a safe transfer of the sample from inside the IVC-rack system to any further processing procedure for analysis of the biological sample outside the IVC-rack system. It is also an object of the present invention to provide a device which is adapted to be used also on existing ventilated shelving systems, allowing the refitting of existing IVC-rack systems.

Method and device for improved hygienic monitoring in IVC systems

IVC rack system comprising a plurality of IVC cages for test animals which are supplied with sterile air, wherein samples of exhaust air from the IVC cages are supplied from sampling points to at least one sentinel cage housing sentinel animals as bio-indicators for the detection of infectious particles within the exhaust air samples, and to at least one particle sampling filter for the identification of pathogens.

IVC rack system and method for detecting infections particles within an IVC rack system

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Garching, Germany

Markus Brielmeier