Edwards Lifesciences Corporation

Other

Edwards Lifesciences Corportion

Mark Van Nest

Derrick Johnson

Brian S Conklin

Louis A Campbell

Da-Yu Chang

Donald E Bobo, Jr

Harvey H Chen

Grace Myong Kim

Myron Howanec, Jr

Paul A Schmidt

Visith Chung

David S Lin

Peng Norasing

Francis M Tran

Isidro L Guerrero

Michael C Murad

Thomas H Chien

Hilda Zhang Fann

Jackie P Lau

John X Wang

Alyssa E Kornswiet

Cindy Woo

Thomas Y Chien

Myron Howanec

Thomas Chien

Donald E Bobo

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

Heart valve stents adapted for post-implant expansion

A valved conduit including a bioprosthetic aortic heart valve connected to a tubular conduit graft forming an ascending aorta. The conduit graft may attach to the heart valve in a manner that facilitates a redo operation in which the valve is replaced with another valve. A sewing ring may be pre-attached to the inflow end of the graft, and then the valve connected to a delivery holder advanced into the graft and secured to the sewing ring. Dry bioprosthetic valves coupled with conduit grafts sealed with a bioresorbable medium can be stored with the delivery holder.

Valved conduit assemblies

Assembly of heart valves and intermediate adapter stent

Methods of assembling valved aortic conduits

One-piece heart valve stents adapted for post-implant expansion

Systems, devices, and methods for leak testing surgical conduit grafts or valved conduits such as aortic-valved conduits with a pressurized gas such as air. Air is non-destructive and especially useful for leak testing conduits that have coatings or sealants that may be functionally impacted when exposed to fluids such as water or saline. Open ends of the conduit are clamped and sealed, and a pressurized gas introduced into an inner lumen thereof. A change in mass flow rate is measured to quantify the leakage. One end of a tubular conduit may be clamped to a fixed manifold, and the opposite end to a manifold slidably mounted to accommodate any conduit elongation when pressurized. The clamping and sealing structure may be pneumatic and/or mechanical, and complementary contoured clamp members may be used to seal a scalloped external sealing ring of an aortic conduit.

Systems for leak testing a valved conduit

Methods of leak testing a surgical conduit

Valved aortic conduits

Surgical heart valves adapted for post-implant expansion

Surgical conduit leak testing

Methods of assembling a valved aortic conduit

Surgical heart valves adapted for post implant expansion

Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a sterile jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. A delivery handle on the end of a shaft couples with the valve holder while the packaging sleeve engages the jar to prevent rotation. The assembly of the packaging sleeve, valve, and holder can then easily be removed from the jar.

Prosthetic heart valve packaging system

Growing community of inventors

Rancho Santa Margarita, CA, United States of America

Mark Van Nest