Hoechst Marion Roussel

Givaudan S.a.

Mark T Yates

Roger A Parker

Kim S Chen

Michael L Edwards

Paul S Wright

Mark J Vaal

Steven J Busch

Simon J Mao

James E Matt

Christopher Todd Simons

Joseph Andrew Kaiser

Matthew Charles Burland

James E Matt, Jr

An oral aroma sampling device includes a mouthpiece which defines an in-mouth surface and an external surface, the in-mouth surface bearing a delivery conduit, and the external surface bearing a manifold in communication with the delivery conduit, the manifold bearing a plurality of capillaries, each of which capillary is the conduit for an aroma substance, the mouthpiece additionally comprising a breathing conduit passing from the external surface to the in-mouth surface. The device is useful as part of a retronasal testing apparatus, which allows a large variety of flavor combinations to be tested quickly and efficiently.

Retronasal device and method

This invention relates to the compounds of 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxyphenylsilyl)methyloxy]phenol, polymorphs thereof and their pharmaceutically acceptable salts, useful as antiatherosclerotic agents.

2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyl-oxy]phenol and

The present invention provides compounds of the formula ##STR1## wherein R is hydrogen or --C(O)--(CH.sub.2).sub.m --Q wherein Q is hydrogen or --COOH and m is an integer 1, 2, 3 or 4;

Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant

The present invention provides compounds of the formula ##STR1## wherein X is selected from the group consisting of ##STR2## Y is thio, oxy or a methylene group; Z is hydrogen or --C(O)--(CH.sub.2).sub.m --Q wherein Q is hydrogen or --COOH and m is an integer 1, 2, 3 or 4;

Substituted phenols and thiophenols useful as antioxidant agents

A method of lowering plasma cholesterol level in a patient with hypercholesterolemia, by administration of a compound of formula (1) ##STR1## wherein: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently a C.sub.1 -C.sub.6 alkyl group;

Method of lowering serum cholesterol levels with

This invention relates to compounds of the formula ##STR1## wherein R.sub.1 and R.sub.6 are each independently C.sub.1 -C.sub.6 alkyl;

Growing community of inventors

Ann Arbor, MI, United States of America

Mark T Yates