Infectious Disease Research Institute

Access To Advanced Health Institute

Mark T Orr

Amit Praful Khandhar

Christopher B Fox

Neal Van Hoeven

Anwar Ahniyaz

Traci Mikasa

Provided herein are nanoalum particles comprising an aluminum salt and a sizing agent, wherein the size of the particle ranges from about 1 nm to 450 nm. Such a nanoalum particles are stable and are amenable to a terminal sterilization step prior to vialing. Compositions comprising the nanoalum particles, and the making and using of the nanoalum particles are also provided.

Nanoalum particles containing a pegylated lipid sizing agent

Provided herein are nanoalum particles comprising an aluminum salt and a sizing agent, wherein the size of the particle ranges from about 1 nm to 450 nm. Such nanoalum particles are stable and are amenable to a terminal sterilization step prior to vialing. Compositions comprising the nanoalum particles, and the making and using of the nanoalum particles are also provided.

Nanoalum particles comprising a PAA sizing agent

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Seattle, WA, United States of America

Mark T Orr