U.S. Smokeless Tobacco Company LLC

Altria Client Services LLC

Mark T Nielsen

Dongmei Xu

Yanxin Shen

Frank Scott Atchley

James A Strickland

Gregory A Pace

David Karl Bried

Lamar Eugene Walters, Ii

Mingwu Cui

Marcos F Lusso

Francis Antoine

Ujwala Warek

Elisabeth Miller

Xiaohong Jin

Kwang Choi

Xue Luo

John R Chipley

Dongmei Xui

Robert F Hart, Iii

Michael L Overbey

David J Watson

The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.

Tobacco plants having reduced nicotine demethylase activity

The present invention featuresnucleic acid sequences such as sequences encoding constitutive, or ethylene or senescence induced polypeptides, in particular cytochrome p450 enzymes, inplants and methods for using these nucleic acid sequences and plants to alter desirable traits, for example by using breeding protocols.

Nicotiana nucleic acid molecules and uses thereof

Provided herein are bacterial strains that are capable of degrading nitrite and/or TSNAs. Also provided herein are methods of using such bacterial strains to degrade nitrite and/or TSNAs.

Nitrite-degrading and TSNA-degrading bacteria and methods of making and using

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Some embodiments of a tobacco product package device can be used to enhance freshness and other characteristics of tobacco products or other products contained therein. Certain features can improve product freshness both during shelf life and during consumer use.

Container device for tobacco articles

The present disclosure describes tobacco varieties having reduced levels of DVTs, methods of making such varieties, and tobacco compositions including such varieties.

Tobacco compositions and methods of making

The present invention provides tobacco inbred plants ALBEX1F and ALBEX1MS. The present invention also provides parts of such plants and products made from those parts. The present invention also includes progeny of the provided plants including hybrids.

Tobacco inbred plants ALBEX1F and ALBEX1MS

Growing community of inventors

Nicholasville, KY, United States of America

Mark T Nielsen