Other

Tonix Pharma Holdings Limited

Zenith Epigenetics Corp.

Mark T Edgar

Stefano Luca Giaffreda

Serena Fabbroni

Michel Chiarucci

Enrico Modena

Henrik C Hansen

Jiahui Chen

Xianghui Wen

Feng Wen

The invention relates to solid crystalline forms of Compound (I), such as e.g., Form VII, including pharmaceutical compositions thereof and processes for preparing crystalline Compound (I), Form VII. Compound (I) modulates or inhibits the activity of BET bromodomain-containing proteins, and is useful in the treatment of diseases such as cancer, inflammatory and cardiovascular diseases.

Method of manufacturing a solid form of a BET bromodomain inhibitor

Disclosed herein is an oxalate salt/co-crystal (tianeptine oxalate) of (RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f] [1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide (tianeptine) as shown in Formula I: 

Tianeptine oxalate salts and polymorphs

An adjustable mount for a flashlight. The adjustable mount having a flashlight receiving body adapted to receive a flashlight. The adjustable mount having a connecting body rotatably connected to the flashlight receiving body at a right angle such that the flashlight receiving body rotates about the connecting body at the connection between the flashlight receiving body and the connecting body. The adjustable mount having a support body rotatably connected to the connecting body at a right angle such that the support body rotates about the connecting body at the connection between the support body and the connecting body.

Adjustable mount for flashlight

Growing community of inventors

Rancho Santa Fe, CA, United States of America

Mark T Edgar