Life Technologies Corporation

Mark Smith

Nephi D Jones

Steven R Kjar

Christopher D Brau

Jacob D Lee

Derik Remmelle West

Norman Ballhause

Paul Thacker

Brycen Mills

Daniel Price

Tony Hsiao

Tony Wentai Hsiao

Brycen Hal Mills

Systems and methods for handheld tubing welders are herein disclosed. In an embodiment, a handheld tubing welder can include a housing configured to be held by a user and a tubing retainer coupled to the housing. The tubing retainer can include a first and second retainer slot configured to receive and retain a first section of a first tubing and a second tubing, respectively. A tubing shifter can be positioned adjacent to the housing and the tubing retainer, the tubing shifter includes a first shifter slot and a second shifter slot that is configured to receive and retain a second section of the first tubing and a second section of the second tubing, respectively. A cutting element can be configured to be movable between the tubing shifter and the tubing retainer to cut the first and second tubing extending between the tubing shifter and tubing retainer. A heating element can be configured to heat the cutting element to a temperature range that allows the first section of the second tubing to thermally weld to the second section of the first tubing.

Handheld tubing welder

A method of installing a flexible bioprocess container in a bioprocessing system having a rigid housing with an interior compartment and extending between a top and an opposing base. The method includes coupling a first surface of the flexible bioprocess container to a moveable platform positioned within the interior compartment of the rigid housing; coupling a second surface of the flexible bioprocess container to the base of the rigid housing; and moving the movable platform relative to the rigid housing and toward the top of the rigid housing so as to at least partially expand the flexible bioprocess container within the interior compartment of the rigid housing.

Methods of installing a flexible bioprocess container in a bioprocessing system

A bioproduction mixing system includes a flexible compartment having a first end, a second end, and a sidewall extending therebetween, a center axis passing through the flexible compartment between the first end and the second end. A helical assembly is disposed within the flexible compartment and is suspended between the first end and the second end, the helical assembly being offset from the center axis of the flexible compartment.

Fluid mixing systems including helical mixing assembly with impeller attachment

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

Systems for cell culture scaling

System and method for cell culture scaling

The present set of embodiments relate to a bioproduction system, method, and apparatus for mixing a fluid. The bioproduction mixing system includes an offset helical assembly having a stabilizer and impeller for mixing a fluid within a flexible compartment The bioproduction mixing system is designed for efficient mixing of the fluid and for use with a variety of different impellers that can be located at different locations according to the volume and shape characteristics of the flexible compartment. The bioproduction mixing system is optimized to eliminate stagnation zones while maximizing bulk fluid flow.

Fluid mixing systems including helical mixing assembly with impeller attachment and methods of use

The present set of embodiments relate a system, method, and various devices for installation of a bioproduction system. The bioproduction system includes a rigid housing having a moveable platform to assist in the installation of a bioprocessing container within. The system also includes mounting systems for a variety of peripherals originating from the flexible container while safeguarding operators. More specifically, the system includes systems and methods for mounting bearings, organizing tube sets, and placement of the flexible container in its proper orientation.

Growing community of inventors

Nibley, UT, United States of America

Mark Smith