Bayer Healthcare LLC

Spectrx, Inc.

Bayer Corporation

Altea Therapeutics Corporation

Mark S Vreeke

Steven C Charlton

Michael R Hatch

Alan Smith

Krishna Kumar

Larry D Johnson

Scott Hoover

J David Farquhar

Teresa Woods

Andrew J Edelbrock

Mark A Samuels

Matthew K Musho

Mark L Faupel

Mary Ellen Warchal-Windham

Christina Blaschke

David Farquhar

Bruce A Flora

Howard A Cooper

Barbara J Mikel

Garrett T Robinson

Allison Minton

Diedre Williams

Alan R Mccleary

An apparatus for lancing skin and collecting a liquid sample. The apparatus having a housing with an outer periphery and a rotatable arm having a lance to puncture the skin. A sample collection area is attached to the arm. The arm of the apparatus rotates from a first position to a second position. As the arm rotates, the lance extends beyond the housing allowing the lance to contact the user's skin and create a lance site. As the arm continues to move to the second position, the lance is brought out of contact with the user's skin and back within the housing while the collection area is brought into position. When the arm is located in the second position, the collection area is in substantially the same location as the lance site on the user's skin.

Swing lance with integrated sensor

Reagents for detecting an analyte are described. A reagent comprises (a) an enzyme selected from the group consisting of a flavoprotein, a quinoprotein, and a combination thereof; and (b) a mediator selected from the group consisting of a phenothiazine, a phenoxazine, and a combination thereof. In addition, reagents having good stability to radiation sterilization are described. Electrochemical sensors and sampling devices comprising such reagents, methods of producing a sterilized device including such reagents, and methods for detecting an analyte which utilize such reagents are described as well.

Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes

Disclosed is an electrochemical sensor for the determination of analytes in body fluids, e.g. glucose in blood. The sensor involves a non-conductive base which provides a flow path for the body fluid with the base having a working and counter electrode on its surface which are in electrical communication with a detector of current. The base and a cover therefore provide a capillary space containing the electrodes into which the body fluid is drawn by capillary action. The counter electrode has a sub-element which contains an electroactive material and is configured in the system (sensor and meter) to provide an error signal when insufficient body fluid is drawn into the capillary.

Electrochemical test sensor

A tissue interface device () suitable for positioning on or about one or more artificial openings in a biological membrane of an organism and for coupling to a monitor and control unit and a vacuum source. The tissue interface device () comprises a housing (), a sensor channel (), and a sensor (). The housing () defines an orifice (), the orifice () having an open inlet port () on the bottom end () of the housing () and a distal end () that is in fluid communication with the sensor channel (). The orifice () is in fluid communication with fluid that flows from the artificial opening formed in the biological membranes. The sensor channel () is for coupling to, and fluid communication therewith, the vacuum source. The sensor () is positioned in the sensor channel () in a flow path of the fluid for sensing a characteristic of the fluid as it flows out from the artificial opening. The sensor generates a sensor signal representative thereof.

Tissue interface device

An alignment device and related systems and methods for aligning at least one apparatus with respect to a surface of a tissue. The alignment device comprises a tissue interface member suitable for positioning on the surface of the tissue and mating with the apparatus to maintain alignment of the apparatus during an operation of the apparatus. The alignment device is useful to align various apparatus that are part of a continuous analyte monitoring system.

Integrated alignment devices, system, and methods for efficient fluid extraction, substance delivery and other applications

Growing community of inventors

Houston, TX, United States of America

Mark S Vreeke