Syngenta Corporation

Mark Robert Sykes

David Anthony Jackson

James Peter Muxworthy

The present invention relates to a compound of the general formula: wherein Ris a 4-pyrimidinyl ring substituted at the 6-position by halo, hydroxy, 2-cyanophenoxy, 2,6-difluorophenoxy, 2-nitrophenoxy or 2-thiocarboxamidophenoxy and wherein Ris any group which can be transesterified to form a methyl ester. The present invention is also directed to a process of preparing said compound.

Process for the preparation of azoxystrobin and analogues thereof

A process for the preparation of a compound of the general formula (I): wherein Ris a 4-pyrimidinyl ring substituted at the 6-position by halo, hydroxy, 2-cyanophenoxy, 2,6-difluorophenoxy, 2-nitrophenoxy or 2-thiocarboxamidophenoxy and Ris any group which can be transesterified to form a methyl ester, which comprises treating a compound of general formula (II): wherein Rand Rhave the meanings given above, with a formylating agent and subsequently treating the formylated product with a methylating agent 

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West Yorkshire, United Kingdom

Mark Robert Sykes