Mevion Medical Systems, Inc.

Affymetrix, Inc.

Xre Corporation

Mark R Jones

James Cooley

Gerrit Townsend Zwart

Eric E McKenzie

David Bradbury

Nathan K Weiner

Christopher Miles

David A Stura

Albert Bukys

Patrick Odoy

Herman Deweerd

Thomas P Regan

Roger DiPaolo

James T Overbeck

Joel M Katz

Tim J Woolaver

Eros Pedroni

Miles S Wagner

Eric Schultz

Robert Silva

Stanley J Rosenthal

Ken Yoshiki Franzen

Ksenia Oleink-Ovod

Michael J Ahearn

Michael Busky

Townsend Zwart

Lionel G Bouchet

Tao Li

Robert Cessac

Joseph Jachinowski

Peter D Honkanen

Adam C Molzahn

Timothy J Woolaver

Oleinik-Ovod Ksenia

Ksenia Oleinik-Ovod

Erik Schultz

Mark Robinson

Yan Liu

Xunjie Yu

Honghai Song

Yan Zhang

Michael Ahearn

Eric Earl Mckenzie

Patrick J Odoy

An example particle therapy system includes a toroid-shaped gantry having a central axis. The toroid-shaped gantry has a cover. The cover includes one or more segments that are rotatable at least partly around the central axis of the toroid-shaped gantry to create an unobstructed opening in the toroid-shaped gantry. The particle therapy system includes a patient couch configured to move relative to a hole in the toroid-shaped gantry, an imaging system coupled to an interior of the toroid-shaped gantry and configured for rotation about the hole in the toroid-shaped gantry, where the imaging system is configured to capture images of a patient on the patient couch, and a nozzle coupled to the interior of the toroid-shaped gantry and configured for rotation about the hole in the toroid-shaped gantry. The nozzle is configured to deliver radiation to a target in the patient based on one or more of the images.

Gantry having a retractable cover

An example particle therapy system includes a gantry having a beamline structure configured to direct a particle beam that is monoenergetic from an output of a particle accelerator towards an irradiation target, where the beamline structure includes magnetic bending elements to bend the particle beam along a length of the beamline structure; and an energy degrader downstream of the beamline structure relative to the particle accelerator, where the energy degrader is configured and controllable to change an energy of the particle beam prior to at least part of the particle beam reaching the irradiation target.

Gantry for a particle therapy system

An example system includes a particle accelerator to produce a particle beam to treat a patient and a carrier having openings including a first opening and a second opening. The carrier is made of a material that inhibits transmission of the particle beam and the carrier is located between the particle accelerator and the patient. A control system is configured to control movement of the particle beam to the first opening to enable at least part of the particle beam to reach the patient, to change an energy of the particle beam while the particle beam remains stationary at the first opening, and to control movement of the particle beam from the first opening to the second opening. The example system also includes an energy degrader that includes at least some boron carbide.

Collimator and energy degrader for a particle therapy system

An example method includes: receiving, from a treatment planning process, information that is based on a dose distribution for an irradiation target; and performing at least one of the following operations: moving structures to trim spots of a particle beam so that the spots of the particle beam approximate pre-trimmed spots for which characteristics are obtained based on the information received; moving structures to produce a trimming curve for a layer of an irradiation target based on a specification of a trimming curve for the layer included in the information received; moving structures to produce a single trimming curve for all radiation fields of an irradiation target based on specifications of the single trimming curve included in the information received; or moving structures based on configuration information for the structures in the information received.

Treatment planning

An example particle therapy system includes a particle accelerator to output a particle beam having a spot size; a scanning system for the particle accelerator to scan the particle beam in two dimensions across at least part of a treatment area of an irradiation target; and an adaptive aperture between the scanning system and the irradiation target. The adaptive aperture includes structures that are movable relative to the irradiation target to approximate a shape to trim part of the treatment area. The part of the treatment area has a size that is based on an area of the spot size.

Adaptive aperture

An example particle therapy system includes a particle beam output device to direct output of a particle beam; a treatment couch to support a patient containing an irradiation target, with the treatment couch being configured for movement; a movable device on which the particle beam output device is mounted for movement relative to the treatment couch; and a control system to provide automated control of at least one of the movable device or the treatment couch to position at least one of the particle beam or the irradiation target for treatment of the irradiation target with the particle beam and, following the treatment of the irradiation target with the particle beam, to provide automated control of at least one of the movable device or the treatment couch to reposition at least one of the particle beam or the irradiation target for additional treatment of the irradiation target with the particle beam.

Automated treatment in particle therapy

An example particle therapy system may include: a synchrocyclotron to produce a particle beam; a scanner to move the particle beam in one or more dimensions relative to an irradiation target; and an energy degrader that is between the scanner and the irradiation target. The energy degrader may include multiple plates that are movable relative to a path of the particle beam, with the multiple plates each being controllable to move while in the path of the particle beam and during movement of the particle beam. An aperture may be between the energy degrader and the irradiation target. The aperture being may be to trim the particle beam prior to the particle beam reaching the irradiation target.

Energy degrader enabling high-speed energy switching

An example device for trimming a particle beam includes: structures made of material that blocks passage of the particle beam, with the structures being configurable to define an edge that is movable into a path of the particle beam; and linear motors that are controllable to configure the structures to define the edge.

Configurable collimator controlled using linear motors

An example particle therapy system includes: a synchrocyclotron to output a particle beam; a magnet to affect a direction of the particle beam to scan the particle beam across at least part of an irradiation target; scattering material that is configurable to change a spot size of the particle beam, where the scattering material is down-beam of the magnet relative to the synchrocyclotron; and a degrader to change an energy of the beam prior to output of the particle beam to the irradiation target, where the degrader is down-beam of the scattering material relative to the synchrocyclotron.

Particle beam scanning

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Reading, MA, United States of America

Mark R Jones