University of California

Other

Hoffmann-la Roche Inc.

Roche Molecular Systems, Inc.

Mark R Green

Ernest S Kawasaki

Robert E Sobol

A holder/carrier temporarily attaches to and supports small items of multiple configurations. Using multiple, flexible straps that are each attached to a support base, the item is enwrapped and retained against the support base. An attachment mechanism, such as a retaining clip, is affixed to the support base, and is utilized to selectively attach the support base, along with the carried, enwrapped item, to a separate supporting structure, such as a waistband, belt or other, suitably-shaped, receiving structures. Additionally, by securing an attachment device that is cooperative with the support base attachment mechanism to another support surface, whether on a permanent or temporary basis, the attachment mechanism may be attached to support surfaces that would not otherwise be suitable.

Multi-strap holder

Methods are provided for detecting carcinoma metastases in selected body tissues and fluids. These methods offer greater than 1,000-fold enhanced sensitivity compared to prior standard diagnostic methods. In one embodiment of the invention, target carcinoma associated nucleic acid sequences are identified for detecting minimal residual disease in lung carcinomas. The methods utilize nucleic acid amplification techniques, preferably, the polymerase chain reaction.

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San Diego, CA, United States of America

Mark R Green