Other

Varian Semiconductor Equipment Associates, Inc.

Mark R Amato

William Davis Lee

James P Bennett

Jillian Reno

Susan L Michaud

Nick Ruebel

Scott Penfold

Paul J Murphy

James D Strassner

Kasegn D Tekletsadik

Daniel J Raymond

Stephen L Spotts

Morgan Evans

Stanislav S Todorov

Daniel Distaso

Jordan B Tye

W Davis Lee

Nandish Desai

David R Timberlake

Armin Huseinovic

Louis P Wainwright

Edward Ivanov

Stephen Sledge

Faye Hendley Elgart

Lauri Reichert

Kyle Schmanke

Lou Wainwright

Nathan Roth

The invention comprises an apparatus and method of use thereof for generating a rare earth from a rare earth oxide, comprising the steps of: (1) dissociating the rare earth oxide and hydrogen gas in a reaction chamber by inductively heating the reaction chamber to greater than 2000° K to form the associated rare earth and water vapor in a reaction process; (2) driving the reaction process forward by removing the water vapor from the reaction chamber by condensing and freezing the water vapor on a first cold trap surface as water ice, where the reaction comprises: REO+3H→2RE+3HO, where REO is a rare earth oxide and RE comprises a rare earth in the rare earth oxide; and/or (3) monitoring the reaction process by monitoring generation of at least one of the rare earth and the water in a control system designed for continuous/semi-continuous operation.

Rare earth extraction apparatus and method of use thereof

The invention comprises a method and apparatus for generating a rare earth from a rare earth oxide, comprising the sequential steps of: (1) reducing temperature about the rare earth oxide to less than zero degrees Celsius; (2) reducing pressure to boil off contaminant water in a powder sample of the rare earth oxide at a molecular escape velocity not disturbing the powdered rare earth oxide; and (3) heating the rare earth oxide to greater than 1000&#xb0; C. in the presence hydrogen gas while optionally: (1) collecting and determining mass of a water product to determine a consumption mass of the starting hydrogen gas in a main reaction process using the equation REO+3H&#x2192;2RE+3HO, wherein 'RE' comprises at a rare earth and (2) injecting replacement hydrogen gas into the main reaction chamber up to the consumption mass.

Rare earth oxide to rare earth extraction apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor of a patient with charged particles, comprising the step of developing a multi-modality treatment plan, the multi-modality treatment plan directing: (1) use of a first beam type to treat a first volume of the tumor, the first beam type a first mass per particle and (2) use of a second beam type to treat a second volume of the tumor, the second beam type comprising a second mass per particle, where the second mass per particle is at least ten percent different than the first mass per particle and the second volume differs from the first volume. The multi-modality treatment plan is optionally formed by selectively merging treatment plans using the respective particle types or is developed using properties of the multiple particle types.

Treatment beam selection apparatus and method of use thereof

The invention comprises a segmented rolling floor apparatus and method of use thereof, such as for use in a charged particle cancer therapy system. The segmented rolling floor comprises a first spool and a second spool, attached to opposite ends of the rolling floor, which cooperatively wind and unwind the rolling floor. The segmented rolling floor circumferentially surrounds a nozzle system penetrating through an aperture in the segmented rolling floor, where the nozzle system is used to deliver charged particles, from an accelerator, to a tumor of a patient. The rolling floor and nozzle systems move at respective rates maintaining the nozzle system in the aperture allowing for a safe/walkable floor while allowing treatment of the tumor as a gantry rotates the nozzle system and delivers protons to the tumor from positions above and below the floor.

Gantry charged particle nozzle system&#x2014;rolling floor interface apparatus and method of use thereof

The invention comprises a method and apparatus for scanning charged particles in a cancer therapy system, comprising the steps of: (1) providing a first and second dipole magnet system and a gap, the gap comprising a common gap length, along a path of the charged particles, within both the first and second dipole magnet systems, the gap comprising a progressively increasing x/y-plane cross-section area from an entrance area of the charged particles into the double dipole magnet system to an exit area of the double dipole magnet system, the x/y-plane perpendicular to a z-axis from a center of the entrance area to a center of the exit area; (2) scanning the positively charged particles along a first axis of the x/y-plane using the first dipole magnet system; and (3) scanning the positively charged particles along a second axis of the x/y-plane using the second dipole magnet system.

Orthogonal double dipole cancer therapy treatment beam scanning apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor, comprising the steps of: (1) a main controller sequentially delivering charged particles from a synchrotron along a first beam transport line, through a nozzle system, and to the tumor according to a current version of the radiation treatment plan; (2) concurrent with the step of delivering, generating an image of the tumor using an imaging system; (3) the main controller automatically generating an updated version of the radiation treatment plan using the image, the updated version of the radiation treatment plan becoming the current version of the radiation treatment plan; and (4) repeating the steps of: delivering grouped bunches of the charged particles, generating an image of the tumor, and automatically generating the updated or current version of the radiation treatment plan with optional intervening doctor approval.

Automated cancer therapy apparatus and method of use thereof

The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.

Ion beam kinetic energy dissipater apparatus and method of use thereof

The invention comprises a method and apparatus for determining state of a positively charged particle, such as a proton, for use in imaging a tumor of a patient prior to and/or concurrent with cancer therapy. The imaging system comprises: (1) a beam transport path of the positively charged particle sequentially passing through a patient, through a first time of flight detector, and, after traversing a pathlength, at least into a second time of flight detector and (2) a beam state determination system using elapsed time between detection at the first and second time of flight detectors and the pathlength to determine a residual beam energy, which, when compared to a known incident beam energy, is used in generation of an image of the tumor. An optional beam energy degrading element increases time differences between the time of flight detectors.

Charged particle cancer therapy beam state determination system and method of use thereof

The invention comprises a method and apparatus for directing protons to a tumor, comprising the steps of: (1) holding a patient with a patient support; (2) providing an imaging system comprising: a rotatable unit at least partially surrounding an axial perimeter of the patient support, a translation guide rail, an imaging source attached to the rotatable unit, and an imaging detector attached to the rotatable unit; (3) translating and rotating the imaging source and the imaging detector relative to the patient support using the translation guide rail and the rotatable unit; and (4) providing an attachment section connected: on a first end to a robotic arm positioning system and on a second end to the patient support and the imaging system, the robotic arm positioning system repositioning, relative to a nozzle system linked to the synchrotron, the attachment system supporting the patient support system and the imaging system.

Integrated imaging-cancer treatment apparatus and method of use thereof

The invention comprises a method and apparatus for using a turning magnet of an accelerator of a cancer therapy system, the accelerator comprising first magnet coils and second correction coils wound about a magnet core where: (1) at a first time, the second correction coils are used to correct a magnetic field, resultant from the first magnet coils, used to turn cations and (2) at a second time, after reversing polarity of the correction coils, the correction coils are used to turn anions and/or electrons, the cations and electrons used to treat a tumor of a patient positioned in a treatment position relative to a treatment beam from the accelerator during the first and second time periods.

Multiple treatment beam type cancer therapy apparatus and method of use thereof

Generally, a method or apparatus for tomographically imaging a sample, such as a tumor of a patient, using positively charged particles positions n two-dimensional detector arrays on n surfaces of a scintillation material or scintillator, respectively. Resultant from energy transfer from the positively charged particles, secondary photons are emitted from the scintillation material and detected by the plurality of two-dimensional detector arrays, where each detector array images the scintillation material. Combining signals from the plurality of two-dimensional detector arrays, the path, position, energy, and/or state of the positively charged particle beam as a function of time and/or rotation of the patient relative to the positively charged particle beam is determined and used in tomographic reconstruction of an image of the sample or the tumor.

Multiple scintillation detector array imaging apparatus and method of use thereof

The invention comprises an apparatus and method of use thereof for using a single patient position during, optionally simultaneous, X-ray imaging and positively charged particle imaging, where imaging a tumor of a patient using X-rays and positively charged particles comprises the steps of: (1) generating an X-ray image using the X-rays directed from an X-ray source, through the patient, and to an X-ray detector, (2) generating a positively charged particle image: (a) using the positively charged particles directed from an exit nozzle, through the patient, through the X-ray detector, and to a scintillator, the scintillator emitting photons when struck by the positively charged particles and (b) generating the positively charged particle image of the tumor using a photon detector configured to detect the emitted photons, where the X-ray detector maintains a position between said the nozzle and the scintillator during the step of generating a positively charged particle image.

Simultaneous/single patient position X-ray and proton imaging apparatus and method of use thereof

The invention comprises a method for treating a tumor of a patient with positively charged particles in a treatment room, comprising the steps of: (1) controlling a cancer therapy treatment system with a main controller, the main controller comprising hardware and software; (2) generating at least one image of the tumor using at least one imaging system controlled by the main controller; (3) using the at least one image and a software coded set of radiation treatment directives, the main controller auto-generating a radiation treatment plan; and (4) the main controller auto-delivering the positively charged particles, via a beam transport system and a nozzle system, from a synchrotron to the tumor according to the radiation treatment plan.

Semi-automated cancer therapy treatment apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor of a patient using positively charged particles, comprising the steps of: (1) providing an approved current version of a radiation treatment plan for treatment of the tumor using the positively charged particles; (2) implementing the current version of the radiation treatment plan using a cancer therapy system comprising a controller linked to a synchrotron; (3) upon identifying an object, using a set of fiducial indicators, in a treatment vector of the radiation treatment plan: generating a modified version of radiation treatment plan and receiving medical doctor approval of the modified version of the radiation treatment plan, the modified version of the radiation plan becoming the current version of the radiation treatment plan; and (4) repeating the steps of implementing and identifying until completion of treatment of the tumor using the positively charged particles.

Treatment beam path verification in a cancer therapy apparatus and method of use thereof

The invention comprises a method for generating a procedure for treating a tumor of a patient using positively charged particles, comprising the steps of: (1) providing a set of treatment goal specifications; (2) generating tomographic images of the tumor using a first set of groups of the positively charge particles delivered from a synchrotron; and (3) a computer implemented algorithm automatically generating a tumor radiation treatment plan, of the tumor using the positively charged particles, using the set of treatment goal specifications and the tomographic images. Optionally, the method automatically updates the radiation treatment plan upon: a detected movement of the tumor relative to surrounding patient constituents and/or upon detection of a previously unforeseen intervening object in a treatment beam path.

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South Hamilton, MA, United States of America

Mark R Amato