Electrochemical Oxygen Concepts, Inc.

Osteobiologics, Inc.

Mark Q Niederauer

James P Daley

Faraidoon Pundole

Mary Ann Walter

Neil C Leatherbury

Daniel J Clarius

Andrew Parker

Michael C Wells

Mark Parker

Tom Woods

Joseph J Moffett

Robert Peyton Wilkes

Alan S Neil

Robert A Tynmann

Steven F Cline

Sabine Cristante

George M Niederauer

A wound treatment system includes a processor coupled to sensor system(s), a power delivery system, an oxygen concentrator coupled to the power delivery system and including an oxygen outlet coupled to a restricted airflow enclosure provided by a dressing and located adjacent a wound site, and a negative pressure system that includes a negative pressure outlet coupled to the restricted airflow enclosure. The processor receives first sensor information from the sensor system(s), and uses the first sensor information to control the power provided from the power delivery system to the oxygen concentrator in order to control an oxygen flow created by the oxygen concentrator and provided through the oxygen outlet to the restricted airflow enclosure. When the processor receives second sensor information from the sensor system(s), it activates the negative pressure system to create a fluid flow from the restricted airflow enclosure and through the negative pressure outlet.

Wound oxygen treatment system

A wound treatment system includes a housing. A processor is located in the housing. A pressure monitoring system is coupled to the processor. A power delivery system is located in the housing and coupled to the processor. An oxygen concentrator is located in the housing and coupled to the power delivery system. The oxygen concentrator includes a plurality of oxygen outlets. The processor is configured to receive pressure information from the pressure monitoring system that is indicative of a pressure in a restricted airflow enclosure provided by a dressing and located adjacent a wound site; and use the pressure information to control the power provided from the power delivery system to the oxygen concentrator in order to control an oxygen flow created by the oxygen concentrator and provided through one of the plurality of oxygen outlets to the restricted airflow enclosure.

Apparatus and methods for controlling tissue oxygenation for wound healing and promoting tissue viability

A wound oxygen supply system includes a chassis that defines an oxygen outlet. an oxygen production subsystem is included in the chassis and coupled to the oxygen outlet. A control subsystem is coupled to the oxygen production subsystem and configured to receive humidity information that is indicative of a humidity experienced by the oxygen production subsystem. The control system then uses the humidity information to control power provided to the oxygen production subsystem in order to control an oxygen flow that is created by the oxygen production subsystem and provided through the oxygen outlet to a restricted airflow enclosure adjacent a wound site.

Wound oxygen supply system

A wound treatment system includes a housing that defines an oxygen outlet. An oxygen production subsystem is included in the housing and coupled to the oxygen outlet. A control subsystem is coupled to the oxygen production subsystem and configured to receive pressure information that is indicative of a pressure in a restricted airflow enclosure that is coupled to the oxygen outlet. The control subsystem then uses the pressure information to control power provided to the oxygen production subsystem in order to control an oxygen flow that is created by the oxygen production subsystem and provided through the oxygen outlet to the restricted airflow enclosure.

Examples include devices, systems and methods related to advanced wound therapy dressings. Specific examples are optimized for use with mobile continuous diffusion of oxygen therapy systems for the localized delivery of oxygen to damaged and healing tissues. Examples may utilize a conduit to deliver therapeutic fluids, including for example oxygen, where the conduit comprises a plurality of apertures or perforations. Examples may also include a spacer material with a plurality of distribution channels in fluid communication with the conduit.

Dressing for wound treatment

A non-invasive tissue oxygenation system for accelerating the healing of damaged tissue and to promote tissue viability is disclosed herein. The system is comprised of a lightweight portable electrochemical oxygen concentrator, a power management system, microprocessors, memory, a pressure sensing system, an optional temperature monitoring system, oxygen flow rate/oxygen partial pressure monitoring and control system, a display screen and key pad navigation controls as a means of providing continuous variably controlled low dosages of oxygen to a wound site and monitoring the healing process. A kink resistant oxygen delivery tubing, whereby the proximal end is removably connected to the device and the distal end with holes or a flexible, flat, oxygen-permeable tape is positioned at or near the wound bed as a means of applying near 100% pure oxygen to the wound site. The distal end of the tube is in communication with the electrochemical oxygen concentrator and wound monitoring system to communicate oxygen partial pressure and, where appropriate, temperature information. A moisture absorbent dressing is positioned over the distal end of the tubing at the wound site and a reduced moisture vapor permeable dressing system is positioned whereby covering the moisture absorbent dressing, distal end of tubing and wound site creating a restricted or occluded airflow enclosure. The restricted airflow enclosure allows the out-of-the-way control and display unit to provide a controlled hyperoxia and hypoxia wound site for accelerated wound healing.

This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.

Method of making biodegradable implant material and products made therefrom

Method of resurfacing a femoral condyle

A handheld materials testing device is provided for measuring compressive properties of a material, preferably articular cartilage in vivo. The device is computer-controlled and provides a readout indicative of the desired compressive property, which in the case of bodily tissue, may be indicative of the state of health of the tissue. The device does not require precise perpendicular alignment and is preferably capable of compensating for force applied by the user against the tissue.

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San Antonio, TX, United States of America

Mark Q Niederauer