Chemocentryx, Inc.

Mark Penfold

Thomas J Schall

Daniel J Dairaghi

Brian E McMaster

J J Wright

Zhenhua Miao

Brett Anthony Premack

Antibodies that bind CXCR7 epitopes, as well as methods of identifying CXCR7 modulators are described.

Antibodies that bind CXCR7 epitopes

Methods for treating CMV or a CMV-related disease are provided that use compounds having the formula: wherein Ar is a substituted or unsubstituted 5&#x2013;14 membered heteroaryl group having from 1 to 5 heteroatoms as ring members; Ris selected from the group consisting of substituted or unsubstituted aryl(C&#x2013;C)alkyl, heteroaryl(C&#x2013;C)alkyl, &#x2014;C(O)R, and &#x2014;C(O)NRR, wherein each Rand Rindependently is substituted or unsubstituted aryl, substituted or unsubstituted aryl(C&#x2013;C)alkyl, substituted or unsubstituted (C&#x2013;C)cycloalkyl(C&#x2013;C)alkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroaryl(C&#x2013;C)alkyl and substituted or unsubstituted hetero(C&#x2013;C)cycloalkyl(C&#x2013;C)alkyl; Ris H or (C&#x2013;C)alkyl; and Zis a substituted or unsubstituted hetero(C&#x2013;C)bicycloalkyl group.

Bicyclic compounds as inhibitors of chemokine binding to US28

Arylamines as inhibitors of chemokine binding to US28

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Mountain View, CA, United States of America

Mark Penfold