Baxter International Inc.

Mark P Sahlin

Richard I Brown

John T Foley

Kyungyoon Min

Timothy J Patno

Kyungoon Min

Blood processing systems and methods separate blood into constituents including a plasma constituent that includes a platelet volume. The systems and methods detect the optical density of the plasma constituent and generate a first output indicative of the optical density. A processing element integrates the first output relative to the volume of plasma constituent and generates an integrated output. The integrated output correlates to the platelet volume. A second processing element generates a third output based, at least in part, upon the integrated output, which comprises parameters for storing the platelet volume.

Blood processing systems and methods which optically monitor plasma opacity

A viewing area in a blood separation chamber is monitored for the presence of an interface region between plasma and cellular blood components. Sensed optical density values for the viewing area are compared to a calibrated threshold value to generate a time pulse output. A calibration element derives the calibrated threshold value based upon either (i) a comparison of a sensed reference optical density value in the viewing area to an expected optical density value for the reference material, or (ii) a sensed optical density value of plasma exiting the blood separation chamber, or both.

Interface detection and control systems and method

Blood processing systems and methods which optically derive the volume

A controller for a peristaltic pump receives as an input pressure P.sub.i sensed at the inlet of the pump. The controller derives a nonlinear scale factor S.sub.Pi that varies as a step function with P.sub.i. The scale factor S.sub.Pi equals a first nonvariable value when P.sub.i lays in a first defined zone of inlet pressures, and equals a second nonvariable value, different than the first nonvariable value, when P.sub.i lays in a second defined zone of inlet pressures different than the first defined zone of inlet pressures. The controller generates a pump speed command based, at least in part, upon S.sub.Pi.

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Hainesville, IL, United States of America

Mark P Sahlin