Other

Duke University

Mark P Donahue

William E Kraus

Elizabeth R Hauser

Lauren R Simel

Embodiments of the present disclosure are directed to a conically-shaped, handheld device that can be used as a computer system input/output device, a gaming system controller, a remote control for various household electronic devices, an interface to a home network, etc. Inputs through the device can be received from various buttons, switches, panels, etc. disposed along a surface of the device as well as sensors embedded within the device. Outputs can be made through speakers, displays, and other transducers also disposed along the surface of the device or embedded with therein. Furthermore, the overall shape and size of the device can be adapted to an individual user through pneumatic bladders disposed within the device.

Ergonomic handheld input/output device

Provided are methods of predicting a trait in a subject including obtaining information about at least a portion of a polynucleotide sequence of the subject, the polynucleotide sequence encoding the acid ceramidase polypeptide, and using the information to predict the expression of the trait in the subject. Further provided are methods of developing a treatment plan for a subject with a disease or condition responsive to exercise. The methods may include obtaining information about at least a portion of a polynucleotide sequence of the subject, the polynucleotide sequence encoding the acid ceramidase polypeptide, using the information to predict a trait selected from maintaining an exercise program and physiological responsiveness to an exercise program, and developing a treatment plan for the subject to treat the disease or condition.

Growing community of inventors

Broomfield, CO, United States of America

Mark P Donahue