Genomic Health, Inc.

Leland Stanford Junior University

Mark Lee

Tara Maddala

Michael R Crager

Diana Cherbavaz

Robert J Pelham

Steven Shak

Dejan Knezevic

William F Novotny

Carl L Millward

Audrey Goddard

Irving L Weissman

Joffre B Baker

Michael C Kiefer

Wayne Cowens

Steve Shak

Kookrin Char

Calvin Jay Kuo

Aharon Kapitulnik

Robert H Hammond

Frederick L Baehner

Tannishtha Reya

Roger W Barton

Stephen S Laderman

Ann F Marshall

Robert Pelham

The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient.

Gene expression profile algorithm and test for determining prognosis of prostate cancer

The present disclosure includes assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for the patient, and likelihood that the patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status.

Method for using gene expression to determine prognosis of prostate cancer

Methods and compositions are provided for the protection of normal cells from cytoreductive therapy that target proliferating cells, by administering an inhibitor of Wnt signaling pathways. Wnt signaling is critically important for homeostasis of the epithelial lining of the adult intestine and other proliferating normal adult tissues.

Use of WNT inhibitors to augment therapeutic index of chemotherapy

Novel superconducting oxide compositions of the formulas (YBa.sub.2 Cu.sub.3.25).sub.a O.sub.z and Y.sub.2 Ba.sub.4 Cu.sub.8 O.sub.20-x (248) are provided which can have an ordered defect structure stacked on one axis. Mi

High-temperature superconductors

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Los Altos Hills, CA, United States of America

Mark Lee