Menarini International Operations Luxembourg S.a.

Bayer Intellectual Property Gmbh

Parion Sciences, Inc.

Mark Jeffrey Edhouse

Scott Alexander Lewis

Philip Jerome Driver

Guy Conwyn Julian Moseley

Michael Ross Johnson

Richard C Boucher

James B Fink

Anthony James Hickey

William Robert Thelin

Max Middleton

Tomas Navratil

Andrew Murray Gow

Klaus Urich

Matthias Burg

Brian Button

Patrick J Ryan

Claus-Peter Reisinger

Stuart Robert Abercrombie

Andreas Kalitzki

Jonathan Hugh Wilkins

Donal Joseph Taylor

Nicholas O Heijne

Paul Boucher

Christopher Edward Butcher

Kathryn Anne Louise Farrell

Samantha Anne Patterson

Brian M Button

Max William Middleton

A fluid management system adapted to automatically supply fluid for injection into a patient is disclosed. The fluid management system includes a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi-dose containers. The fluid transfer system connects an outlet of these containers to the injector which withdraws a fluid from the containers via the fluid transfer system and injects the fluid to an administration device at the patient. The fluid management device includes at least one rotating carousel having a vertical axis of rotation, at least two container holders attached to the rotating carousel and adapted to position the container vertically with a septum covered end facing downwards, and a spike holder mounted below the rotating carousel and oriented so the spike holder axially aligns a spike connected to the spike holder with the axis of the container.

Fluid management device having rotating carousel with container holders for vertically positioning a container during automated spiking and injection into patient

A device for the automatic injection of doses of a drug compound is described. The device has a sliding sheath which, when depressed with its front end against the injection site, interacts with cam means to activate triggering of a plunger, thus controlling delivery of a drug dose. Plunger guide means are provided for controlling the triggering sequence and means for arming the device in the dose delivery condition. Automatic needle re-sheathing and resetting of a lock-out condition after each dose is delivered are also provided.

Device for automatic injection of drug doses

A two-dose autoinjector for a medicament wherein the locking and releasing of the drive spring of the autoinjector is controlled through stepped guides with ramps for two successive slidings of slides operated by the spring and connected with the syringe and plunger. The guides and the slides are pivotable relative to one another and the sliding direction, while the syringe can only slide axially. To enable or disable the sliding of the slides within the guides an angularly angularly mobile arming member is provided formed with a guide track substantially equal to that of the stationary member where the guides are formed.

Device for the automatic injection of two doses of a medicament

An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.

Aerosol delivery systems, compositions and methods

A device for the automatic injection of doses of a drug is described. The device has a slide and cam means, a syringe unit with a piston, and guide means. The axial movement of the slide initiated by a user by depressing its front end against an injection site, causes an angular displacement of the cam means that, in cooperation with the guide means, controls movement of the syringe piston and therefore administration of a drug dose.

Growing community of inventors

Cambridge, United Kingdom

Mark Jeffrey Edhouse