Acist Medical Systems, Inc.

Eli Lilly and Company

3com Corporation

Nitto-denko Corporation

Northwestern University

General Binding Corporation

Quidel Corporation

Altea Therapeutics Corporation

Carrier Corporation

Acco Brands Corporation

Nanosphere, Inc.

Altea Therapeutic Corporation

Antares Pharma, Inc.

Passport Technologies, Inc.

Mark James Fisher

Jeremiah P O'Leary

Joseph Graceffa

Stephen Wilson Braun

Uros Kascak

Anastasios G Karahalios

Traci J Barron

Khader Mohiuddin

David J Hajicek

Martin G Hieb

Zoran Novakovic

Manfred Maiers

Robert Kim

Richard A Oftedahl

Tom Westberg

Jonathan Eppstein

Shu Kun Chang

Stuart McRae

David Farquhar

Bernadette Messier

David M Kelso

Peter Hotkowski

Kunal Sur

Frank A Todaro

Samuel P Amdahl

Rajendra K Shah

Scott Harold Wilson

Andrew Burroughs

Benjamin Rush

Mark Alexander Jones

Stephen Dylan Berry

Michael A Roher

Mehran Mojarrad

Jonathan A Eppstein

George Kyaw Soe Maung Aye

Sumir Kapur

Iain Roberts

John Grimley

James Matthew Collins

Craig Field Sampson

Tim Patno

Loren J Lantz

Adolfo Menendez, Jr

Lawrence Lunzer

Niels Clausen-Stuck

Volker Roos

Karen Kensok

Erin Melissa Koch

Wendy E Bowerman

Regina Spiehl

Erin Koch Henkel

Zaheer Parpia

Marc Kullberg

S Kuen Chang

Scott Massing

Kuen Chang

Timothy D Byland

Chad M Johnson

Lawrence Markus

John Michael O'Fallon

Traci Jo Barron

Timothy Patno

Stacey Hsu-Wen Chang

Ashley Danielle Cramer

Jacqueline R Groves

James G Tappel

Richard Charles Thorne

George Kyaw Soe Maung

David Hixson

Traci Barron

Stuart McRAE

John Michael O'fallon

Jeremiah Peter O'LEARY

Steven Wilson Braun

Martin G Heib

Roos Volker

Lawrence W Markus

Ashley D Cramer

Devices for use in extracting an analyte of interest from a sample are described. In one embodiment, a device is comprised of a first plurality of chambers, where one or more chambers in the plurality of chambers has a deep end and a shallow end with a depth d. A channel disposed between at least two adjacent chambers in the plurality of chambers has a depth greater than d. The dimensions of the chamber and channel provide control of fluid movement in the device, particularly when introducing fluid into the device for its use and during use of the device.

Device with controlled fluid dynamics, for isolation of an analyte from a sample

An example method includes receiving, within a graphical user interface (GUI) of a medical fluid injection system, a selection of a particular user, providing, within the GUI, a display of a plurality of selectable options, each option including at least a respective graphical symbol, wherein each respective graphical symbol comprises a respective non-textual icon that is a graphical representation of a respective anatomical location associated with the medical procedure, each respective anatomical location comprising one of a left coronary artery, a right coronary artery, or a left ventricle and aorta, retrieving one or more customized injection parameters that have respective values customized for the particular user based on one or more preferences of the particular user, and displaying, within the GUI, the one or more customized injection parameters.

Customizable medical fluid injection system and method

A transdermal permeant delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.

Transdermal porator and patch system and method for using same

A disposable fluid connector includes a first single-use tubing component having proximal and distal ends and a second single-use tubing component having proximal and distal ends, where the first single-use tubing component and the second single-use tubing component are each usable only for a single patient procedure. The disposable fluid connector also includes a connection comprising an electrical connector that is configured to electrically connect the connection to both a powered injector and to an external medical device, where the disposable fluid connector comprises a disposable cassette including a portion that is non-removably attached to both the first single-use tubing component and the second single-use tubing component.

Disposable fluid connector having multiple tubing components and an electrical connector

A device for extraction or isolation of an analyte, such as a nucleic acid, a protein, or a cell, from a sample, and in particular from a biological sample is described. Methods of using the device are also described.

Device for isolating an analyte from a sample, and methods of use

One embodiment provides a method of using contextual lighting to assist a user of a medical fluid injection system. In this embodiment, the method includes providing a lighted display in proximity to a component of the injection system during setup of the medical fluid injection system. If the user has properly performed a setup function that is associated with the component of the injection system, the method further comprises providing a first visual indication on the lighted display. If the user has not properly performed the setup function that is associated with the component of the injection system, the method further comprises providing a second visual indication on the lighted display.

Medical fluid injection system

Medical fluid injection system and method for guided setup

A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.

A fluid injecting device () generally including a fluid delivery assembly () and a needle-free injecting assembly (). The fluid delivery assembly () delivers or transfers the fluid medicine from a cartridge () into the needle-free injecting assembly () for injecting into a patient. A drive train () applies a force to a piston () inside the cartridge () during the delivery of the fluid to the needle-free injecting assembly () to prevent adhesion or static friction between the piston () and the cartridge (). In addition, sensors can be used to help ensure the proper amount of dosage is transferred to the needle-free injecting assembly, conserve power, reduce leakage during disassembly, among other functions.

Needle-free injection device

Binding element

A plurality of binding elements, each of a substantially uniform thickness, the fingers being looped over and coupled to the spine such that the inner surface of the fingers is disposed against the inner surface of the spine by an adhesive when assembled. In an embodiment, at least a portion of the outer surface of the binding element is resistant to a more permanent attachment to the adhesive such that the plurality may be stacked together, and successively decoupled or removed for insertion into a stack. The binding elements may include score lines or bends in the fingers to provide a rounded closed loop structure; optional gussets in the bends inhibit straightening of the fingers. The fingers optionally include variations in cross-section along the length to relieve certain stresses to inhibit the looped finger. The binding elements optionally include structure for facilitating interaction with an automating binding process.

Binding elements and plurality of binding elements particularly suited for automated processes

A medication dispensing apparatus having a manually operable plunger axially shiftable relative to the apparatus housing. The plunger is pullable relative to the housing in a proximal direction to cock the apparatus, and when the plunger is then manually pushed back toward the housing, a piston within a medicine container of the apparatus is shifted to force medication from a needle assembly at the distal end of the apparatus. The medication dispensing apparatus also includes a priming mechanism which is operated by rotating an externally accessible driver portion to prime the apparatus for use, which priming can be performed whether or not the apparatus is in a cocked state.

Medication dispensing apparatus configured for rotate to prime and pull/push to inject functionality

Disposable microporation porator

Growing community of inventors

Highland Park, IL, United States of America

Mark James Fisher