Cobe Laboratories, Inc.

Gambro, Inc.

Mark J Brierton

John J Kappus

Victor D Dolecek

Jeffrey J Blakeslee

David R Shouldice

Coy Toavs

Russell Hempstead

Leon E Bilodeau

Kyungyoon Min

Christopher J Wegener

Daniel R Boggs

Benjamin E Kusters

An extracorporeal blood processing system including a disposable assembly that has integral fluid passageways. A blood removal conduit and a blood return conduit are interconnected with the integral fluid passageways. A diaphragm is mounted in the disposable assembly and is removably attachable to a sensor via a number of connection devices. In one embodiment, the sensor may include a transducer that is capable of measuring the force exerted on the diaphragm. The corresponding force may be correlated to a pressure of fluid in either the blood removal conduit and/or the blood return conduit.

Extracorporeal blood processing system

An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.

Extracorporeal blood processing methods and apparatus

An extracorporeal blood processing system which includes a disposable assembly. The system includes a disposable assembly that has integral fluid passageways. A blood removal conduit and a blood return conduit are interconnected with the integral fluid passageways. A diaphragm is mounted in the disposable assembly and is removably attachable to a sensor via a number of alternative connection devices. In one embodiment, the sensor may include a transducer that is capable of measuring the force exerted on the diaphragm. The corresponding force may be correlated to a pressure of fluid in either the blood removal conduit and/or the blood return conduit.

A temperature-controlled centrifuge in which a heat exchanger is attached to the bottom portion of the centrifuge bowl to remove heat from the bowl and materials within the bowl interacting therewith. In one embodiment, a heat exchange plate having a plurality of substantially annular channels is appropriately attached to the bottom of the centrifuge bowl and has a surface which is thus substantially coextensive therewith. Each of these channels are positioned at different radial distances from the central axis of the heat exchange plate and each extends substantially about such axis. An appropriate heat transfer medium may thus be circulated through each of these channels to thereby substantially control a temperature across the entire bottom of the bowl. The heat transfer medium may be provided to each of the channels by a common feed inlet which also allows for the use of flow regulators where appropriate, and the heat transfer medium may also thus be removed from the channels by a common dump line. Consequently, coaxial conduits may interact with the bottom portion of the heat exchanger for interconnection with the common feed and dump lines.

Temperature controlled centrifuge

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Littleton, CO, United States of America

Mark J Brierton